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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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Is Finding The Infection Site So Difficult?

hello doctor,
my mother has stage 3/4 heartfailure, she is 54 years old. in the past few months her crp levels are very high 60plus but the docs say they dont want to treat it until they know the infection site they have done many ct and mri scans aswell as blood cultures but they havent found teh site. just recently they done a toe aswell but still cant find the infection site. by the way the blood cultures come back negative.
now my mothers spleen has enlarged. what is going on and why dont the doctors just administer antibiotic even if they dont know the infection site

ps my mother had a crt d installed 6 months ago but in the toe the docs dont think that the pacemakers leads are infected
help plz
Fri, 18 Nov 2016
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Cardiologist 's  Response
in case if the pace maker leads were infected her tlc /dlc counts would have increased
her blood culture and sensitivity test must have been positive for bacteria
any infection in body is frequently associated with rise in body temp(pyrexia) as you is a patient of chf on icd
prophylactic antibiotic therapy can be given for 5 days
tab ceftum 500 twice daily
tab linid 600 twice daily
crp is an indicator of infection but its a very old test and a non specific marker of infection
as her spleen has increased in size now i would suggest you to go for
a repeat
a serum procalcitonin (a very specific test for indicating infection)
blood r m
blood c n s
esr
tlc
dlc
cbc
urine r n m

a combined analysis of these tests can be helpul in reaching a conclusion
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Is Finding The Infection Site So Difficult?

in case if the pace maker leads were infected her tlc /dlc counts would have increased her blood culture and sensitivity test must have been positive for bacteria any infection in body is frequently associated with rise in body temp(pyrexia) as you is a patient of chf on icd prophylactic antibiotic therapy can be given for 5 days tab ceftum 500 twice daily tab linid 600 twice daily crp is an indicator of infection but its a very old test and a non specific marker of infection as her spleen has increased in size now i would suggest you to go for a repeat a serum procalcitonin (a very specific test for indicating infection) blood r m blood c n s esr tlc dlc cbc urine r n m a combined analysis of these tests can be helpul in reaching a conclusion