HealthCareMagic is now Ask A Doctor - 24x7 | https://www.askadoctor24x7.com

question-icon

Suggest Treatment For Recurrent Blisters When Diagnosed With Bullous Pemphigoid

default
Posted on Wed, 16 Sep 2015
Question: my Husband has had bullous pemphioid since 6 XXXXXXX 2015 We have been all over northwest Arkansas. been treated with high levels of predisone and antibotics. We think it is going to clear up and then it is back again all over. some blisters are as big as a soft ball. He has never been totally free of the blister. he is getting weaker by the day. at night he has some kind of seziures. We are at our witys end. can you give us some kind of hint.
doctor
Answered by Dr. Divya Agarwal (37 minutes later)
Brief Answer:
topical corticosteroids are beleived to be more efficacious

Detailed Answer:
hi,
Scientifically, topical corticosteroids are known to be better than treating patients with systemic corticosteroids.
Topical agents like clobetasol0.05% can be applied on all the lesions and the dose can be gradually decreased as the patient achieves remission.
However if due to certain problems topical agents cannot be used, and oral corticosteroids are being used, there is indication for starting immunosuppressive agents which are known to be steroid sparing like Azathioprine, Mycophenolate mofetil, or Methotrexate.
These drugs take time to take action ,how ever help in bringing down the dose of steroid, and bringing the disease into remission.
In certain cases not responsive to the above regimens, and completely refractory, there are biologic drugs like rituximab and iv immunoglobulin.

You can discuss these options with the treating doctor.

Regards
Above answer was peer-reviewed by : Dr. Prasad
doctor
default
Follow up: Dr. Divya Agarwal (30 minutes later)
we have used the topical creams. You said nothing about Mayo. What happends if you can't control this
doctor
Answered by Dr. Divya Agarwal (4 hours later)
Brief Answer:
mayo has some of the best doctors.

Detailed Answer:
mayo has some of the best doctors.
you can consult there.
The comprehensive treatment needs to be face to face with the doctor.
Note: For further information on diet changes to reduce allergy symptoms or to boost your immunity, Ask here.

Above answer was peer-reviewed by : Dr. Raju A.T
doctor
Answered by
Dr.
Dr. Divya Agarwal

Rheumatologist

Practicing since :1999

Answered : 659 Questions

premium_optimized

The User accepted the expert's answer

Share on

Get personalised answers from verified doctor in minutes across 80+ specialties

159 Doctors Online

By proceeding, I accept the Terms and Conditions

HCM Blog Instant Access to Doctors
HCM Blog Questions Answered
HCM Blog Satisfaction
Suggest Treatment For Recurrent Blisters When Diagnosed With Bullous Pemphigoid

Brief Answer: topical corticosteroids are beleived to be more efficacious Detailed Answer: hi, Scientifically, topical corticosteroids are known to be better than treating patients with systemic corticosteroids. Topical agents like clobetasol0.05% can be applied on all the lesions and the dose can be gradually decreased as the patient achieves remission. However if due to certain problems topical agents cannot be used, and oral corticosteroids are being used, there is indication for starting immunosuppressive agents which are known to be steroid sparing like Azathioprine, Mycophenolate mofetil, or Methotrexate. These drugs take time to take action ,how ever help in bringing down the dose of steroid, and bringing the disease into remission. In certain cases not responsive to the above regimens, and completely refractory, there are biologic drugs like rituximab and iv immunoglobulin. You can discuss these options with the treating doctor. Regards