
Suggest Treatment For Severe Anxiety

Consultation
Detailed Answer:
Hello, and thanks very much for your question.
I'm sorry you are suffering so much from anxiety. Let me give you my thoughts.
First, let me discuss medications. You say you have tried several antidepressants and benzos. Can you be a bit more specific? Have you tried, for at least 4 weeks (at least this long to be considered an adequate trial), one of each class of SSRI, SNRI, TCA, MAOi, and atypical (Remeron, Wellbutrin)? Have you tried long-acting (Valium, Klonopin) and moderate-acting (Ativan) benzos?
Regarding therapy, as you likely well know given your profession, CBT is regarded as the most effective for anxiety. How long did you try CBT?
With these answers I can be more helpful with my advice.
Dr. Sheppe


Sincerely,
Ashley
Followup
Detailed Answer:
This certainly appears to be a treatment-refractory situation. What doses of benzos were you using? Typically these work well for anxiety at least in the short term -- I'd be surprised if even benzos at adequate doses were not touching your anxiety. The long-acting ones, as you ask, are Valium and Klonopin, both of which it appears you have tried. Gabapentin and Vistaril are also sometimes used for immediate anxiety relief. Some long-term medications you can consider at this point are Remeron and Seroquel, both of which are sometimes effective in anxiety. Electroconvulsive therapy, sometimes seen as a last resort treatment, is unfortunately not effective for anxiety disorders.
When I've gotten this far with medications with my patients, and nothing seems to be working, I begin to consider personality disorders, in your case something like avoidant personality disorder, dependent personality disorder, or obsessive-compulsive personality disorder. These are not improved with medication, but (for better or worse) take years of psychodynamic psychotherapy, even psychoanalysis, to treat effectively. Has this possibility been explored with you yet?
Dr. Sheppe

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