Suggest Treatment For Severe Nausea And Epigrastric Pain
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Detailed Answer:
I read your question carefully and I understand your concern.
I have to say that yours is indeed a difficult case, with many drug interactions and failures to consider.
Regarding nausea I would say you already take some of the most potent medication against it out there. The only medication I could add which could be tried would be Domperidone, I wonder if you have already tried it. I would also reconsider the necessity of fentanyl and dilaudid as they are opioids and both have the potential for causing nausea themselves.
As for spasms, I must say I am not that crazy about the use of baclofen and tizanidine. They are antispasmodic medication true, but are generally used for spasms of skeletal muscle not smooth muscle like in the stomach and intestine. Alternatives which are used for intestinal spasms are dicyclomine, hyoscyamine, mebeverine (fewer side effects than the first 2) or the old papaverine. I am listing several and not only one of them in case you have already tried some, but of course they are not taken all together.
I hope to have been of help.