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Suggest Treatment For Withdrawal Symptoms Of Effient

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Posted on Thu, 25 May 2017
Question: Sir I had a cardiac stent two years ago and have stayed on the Effient product all of that time. I recently asked if I could get off the Effient and I was told that was ok. I was going to continue with low dose aspirin. I have now experienced continuing blood pressure problems (quite high) and associated dizziness etc. I have not had any blood pressure issues whatsoever prior to this,and I assume this is some type of "withdrawal" problem. Could I get back on the Effient (which worked well) safely? My doctor apparently isn't aware of withdrawal issues with anticoagulants.
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Answered by Dr. Ilir Sharka (1 hour later)
Brief Answer:
I would recommend as follows:

Detailed Answer:
Hello!

Welcome back again on HCM!

Regarding your concern, I would agree with you that your complaints could be related to Effient withdrawal syndrome.

It is known that in some susceptible persons this drug interruption can lead to increased anxiety and indigestion. From the other hand the fact that all your complaints began after switching from Effient to low dose aspirin, is another possible argument in favor of this cause.

Anyway, before coming to this conclusion, I would recommend consulting with your attending physician and performing some tests to exclude other possible underlying causes that may mimic this clinical scenario:

- a resting ECG
- a Doppler ultrasound of the cervical arteries (dizziness could be a sign of low blood flow to the brain or narrowed cervical arteries)
- complete blood count for anemia
- thyroid hormone levels for thyroid dysfunction
- liver and kidney function tests
- fasting glucose
- blood electrolytes for possible imbalance.

If all the above tests result OK, then you should consider Effient interruption as the main cause of your complains. In such case you can switch again to Effient. It is quite safe.

Hope to have been helpful!

I remain at your disposal whenever you have any other questions!

Kind regards,

Dr. Iliri
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Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar
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Answered by
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Dr. Ilir Sharka

Cardiologist

Practicing since :2001

Answered : 9545 Questions

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Suggest Treatment For Withdrawal Symptoms Of Effient

Brief Answer: I would recommend as follows: Detailed Answer: Hello! Welcome back again on HCM! Regarding your concern, I would agree with you that your complaints could be related to Effient withdrawal syndrome. It is known that in some susceptible persons this drug interruption can lead to increased anxiety and indigestion. From the other hand the fact that all your complaints began after switching from Effient to low dose aspirin, is another possible argument in favor of this cause. Anyway, before coming to this conclusion, I would recommend consulting with your attending physician and performing some tests to exclude other possible underlying causes that may mimic this clinical scenario: - a resting ECG - a Doppler ultrasound of the cervical arteries (dizziness could be a sign of low blood flow to the brain or narrowed cervical arteries) - complete blood count for anemia - thyroid hormone levels for thyroid dysfunction - liver and kidney function tests - fasting glucose - blood electrolytes for possible imbalance. If all the above tests result OK, then you should consider Effient interruption as the main cause of your complains. In such case you can switch again to Effient. It is quite safe. Hope to have been helpful! I remain at your disposal whenever you have any other questions! Kind regards, Dr. Iliri