HealthCareMagic is now Ask A Doctor - 24x7 | https://www.askadoctor24x7.com

Suggest Ways To Manage The Vomiting And Diarrhea After Taking Metformin

Posted on Mon, 9 Feb 2015

Question: I'm a type 2 diabetic, I was given bydureon which was taken last Thursday, and metformin TR 500 mg with dinner. I have had allergic reactions to Metformin in the past which caused vomiting and diaherrea. After taking 500 mg of Metformin on Thursday evening I had diaherrea all the next day. I took a second dose on Friday evening. Since Saturday I have been vomiting and diahrerra all day and night. I'm sure the metformin is out of my system now, so it must be the bydreon causing the symptoms I have described. If I take one bit of food, I start to vomit. I need to know what to do now, I have had no food since Friday.

Answered by Dr. M. Vamsi Krishna (23 minutes later)

Brief Answer:
Vomiting and diarrhea are side effects bydureon

Detailed Answer:
Hi dear
good day
I can understand your concern in my opinion the medication you are taking are metformin and long acting exinatide this is also called as bydureon
the main action of drug bydureon is to increase a hormone called incretin in your blood
this hormone incretin will not allow food to go down into the intestine quickly so the food will stay in stomach for long time and giving a feel of nausea for patients

similar symptoms can be seen with metformin but when compare with bydureon it will be very mild.

so in this kind of conditions usually I will ask my patients to reduce the dose of bydureon to lowest possible dose and prescribe some medication to reduce gastritis kindly meet your doc and discuss the condition .
hope this satisfies your query

regards
Dr Vamsi XXXXXXX
Diabetologist

Above answer was peer-reviewed by : Dr. Vinay Bhardwaj

Follow up: Dr. M. Vamsi Krishna (1 hour later)

The byduron last for 7 days, and I started it on Thursday. I cannot reduce it yet, as I still have this dose of 7 days in me right now. I don't just have nausea, I'm throwing up the minute I eat any food. I throw up what I had 2 hours ago. So, for you to stay the food stays in the stomach longer, I now see that. Is there anything I can take to stop throwing up? I will be contacting my doctor first thing in the morning, but not being able to eat is awful. I have not had solid food/ or any food since Friday.

Answered by Dr. M. Vamsi Krishna (7 hours later)

Brief Answer:
Take very small meals with 2 hrs gap

Detailed Answer:
hi dear
there are few solutions for your problem.
usually most of my patients are well tolerating the medicine by the end of 2 wks
2.ask your doctor to change to milder form of drugs with similar action like victoza
3.some supportive medications can be tried like PPI to reduce Gastitis and anti emetics for better symptomatic Response
4.dont lie down immediately after taking food
Hope this things will help you
kindly speak with your doctor for further management of the condition.

don't forget to take sufficient fluids

regards
Dr XXXXXXX

Note: For further follow-up, discuss your blood glucose reports with our diabetologist. Click here.

Above answer was peer-reviewed by : Dr. Shanthi.E