What Are Skin Side Effects, Contraindications And Treatments For Someone With Addison's Disease?
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Addison's disease occurs when the adrenal glands do not produce enough of the hormone cortisol and, in some cases, the hormone aldosterone.
The disease is characterized by weight loss, muscle weakness, fatigue, low blood pressure, and sometimes darkening of the skin in both exposed and non-exposed parts of the body.
Skin changes in Addison's disease are: there will be areas of hyperpigmentation, or dark tanning, it can be seen in covering exposed and non-exposed parts of the body. This darkening of the skin is most visible on scars, skin folds, pressure points such as the elbows, knees, knuckles, toes, lips, and mucous membranes. Sometimes paleness is also seen.
Treatment of Addison's disease involves replacing, or substituting, the hormones that the adrenal glands are not making. Synthetic glucocorticoid and mineralocorticoid are used. If receiving mineralocorticoid replacement therapy, are usually advised to increase their salt intake.
Addison’s patient undergoing surgery should have pretreatment with synthetic glucocorticoid and saline the previous night.
During pregnancy, in case nausea and vomiting, oral drugs can be replaced by injections.
Contraindication to treatment depends on the drug given and any associated diseases from which you are suffering. It will be nice if you mention your past history of disease and also the drug history.
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