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What Are The Side Effects Of Alendronate?

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Posted on Thu, 7 Sep 2017
Question: I have osteoporosis and was prescribed Alendronate 70mg tabs. Then adviced not to take them. Infusion was prescribed then. I have verices in esophagus. What side effects can I expect?
doctor
Answered by Dr. Dr. Gopal (1 hour later)
Brief Answer:
Alendronate can cause severe gastritis.

Detailed Answer:
Hi I am Dr Gopal Goel Orthopedic Surgeon.
Alendronate can cause severe gastritis and since you have esophageal varices , you may have bleeding in gut due to alendronate. This effect of alendronate is only local so other medicine of this group can be given through injections. That is probably the reason why injection( infusion) was prescribed.
Thanx for the question. Please feel free to ask any other question.
Above answer was peer-reviewed by : Dr. Nagamani Ng
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Follow up: Dr. Dr. Gopal (8 hours later)
Am I to understand by your reply that it is safe to have the infusion performed and the side effects, which was not addressed, are considered safe and tolerable
doctor
Answered by Dr. Dr. Gopal (3 minutes later)
Brief Answer:
What particular medicine is being infused?

Detailed Answer:
Hi
Please let me know which particular medicine is being infused. Some medicines like Inj Ibandronate can be given without any major side effects while medicines like zolidronic acid are to be given with lot of caution.
Thanx
Above answer was peer-reviewed by : Dr. Vaishalee Punj
doctor
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Follow up: Dr. Dr. Gopal (15 minutes later)
I am not sure what medicine it is. I only know that it is for Reclast Infusion.
doctor
Answered by Dr. Dr. Gopal (4 minutes later)
Brief Answer:
It is zolidronic acid.

Detailed Answer:
Hi
Reclast is zolidronic acid.
Normally I would fet kidney function tests and if they are normal, I will go for infusion.
Before infusion I give one bottle of normal saline to adequately hydrate my patients. Fever is to be expected after infusion - will be controlled with paracetamol only.
All the best
Thanx
Note: For further queries, consult a joint and bone specialist, an Orthopaedic surgeon. Book a Call now.

Above answer was peer-reviewed by : Dr. Vaishalee Punj
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Answered by
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Dr. Dr. Gopal

Orthopaedic Surgeon

Practicing since :1983

Answered : 1537 Questions

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What Are The Side Effects Of Alendronate?

Brief Answer: Alendronate can cause severe gastritis. Detailed Answer: Hi I am Dr Gopal Goel Orthopedic Surgeon. Alendronate can cause severe gastritis and since you have esophageal varices , you may have bleeding in gut due to alendronate. This effect of alendronate is only local so other medicine of this group can be given through injections. That is probably the reason why injection( infusion) was prescribed. Thanx for the question. Please feel free to ask any other question.