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What Are The Withdrawal Symptoms Of Baclofen, Stablon And Stresnil?

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Posted on Sat, 23 Apr 2016
Question: my dad has been taking stablon 12.5mg,baclofen 10 mg thrice a day
and stressnil 0.5mg in night since last 10 months for alcohol deaddiction and depression.
since then he has been away from alcohol and depression too is not there.

so is it a good time to stop medication?
and what should be the way to reduce dosage so he does not have withdrawal symptomms?
doctor
Answered by Dr. Dr. Chintan Solanki (33 minutes later)
Brief Answer:
stop one by one under doctor's supervision

Detailed Answer:
Hello XXXXXXX

Thanks for writing back to us.

Stablon 12.5 mg is low dose. If he is better since more than 6 months in depression, stablon can be taken half (6.25 mg) for 20 days and then stopped.

Baclofen as such is muscle relaxant. It can be decreased 10 mg every 15 days.

Both of these drugs are not associated with withdrawals with slow tapering.

Stressnil 0.5 mg contains alprazolam. It may be difficult to stop it suddenly. It should be continued until other two medicines completely stop. After than dose can be reduced to 0.25 mg for 1 month before stopping and simultaneously other measures for good sleep should be followed.
I would recommend following 'sleep hygiene'.

These are some measures called which would help in sleep. You can find the same in below link.

sleepfoundation.org/ask-the-expert/sleep-hygiene

Drinking a cup of warm milk before going to bed helps in 30-40% of patients and they do not need medicines as per my clinical experience.

You can follow recommendations after discussing with his treating doctor.

Hope I have answered your query, I will be happy to help further.
Regards,
Dr.Chintan Solanki.

Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar
doctor
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Follow up: Dr. Dr. Chintan Solanki (10 minutes later)
so first,one of stablon and baclofen should be reduced and stopped ,then the other one?

or both can be reduced simultaneously?
doctor
Answered by Dr. Dr. Chintan Solanki (1 minute later)
Brief Answer:
both simultaneously

Detailed Answer:
Hi,

Thanks for follow up.

Both stablon and baclofen can be reduced together. Stablon will stop first and baclofen later in his case.

Feel free to discuss further.

Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar
doctor
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Follow up: Dr. Dr. Chintan Solanki (50 minutes later)
thanks for your answer. i have one more question.

do these antidepressants have permanent effect?

what i know is,these increases serotonin in brain which cure depression.

but what happens when a person stop taking it? how does serotonin comes then?
doctor
Answered by Dr. Dr. Chintan Solanki (2 hours later)
Brief Answer:
it very complicated and hidden phenomenon

Detailed Answer:
Hi,

Thanks for your curious question.

Actually serotonin alone is not responsible factor for depression. There are lots of other neurotransmitters, hormonal, biological, genetics, psychological and social factors are involved in etiology of depression. We call it bio-psycho-social model.

In 50% of the patients with depression first episode is last episode. In remaining second episode occurs. Among them 50% have 3rd episode.

With medicines, social and psychological factors matter. In your father's case I guess alcohol is also related factor.

Drugs are not making new serotonin they just make the changes at cell level to make serotonin more effective. In many patients even after stopping the medicines these biological changes remain permanent. In other patients with other factors relative serotonin deficiency may be created again.

Your father has responded well to medicine. No need to worry. In any case by chance if he will have problem, he can be treated easily.

Ask him to maintain healthy lifestyles. This includes regular daily exercise (walking or running), hygienic food habits (no junk food, no fatty food, preferably only home-made food with law salt and fat with more fruits and vegetables) and timely scheduled sleep. Yoga- meditation can also help.

Hope this answer clarifies your doubts.
Note: For further guidance on mental health, Click here.

Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar
doctor
Answered by
Dr.
Dr. Dr. Chintan Solanki

Psychiatrist

Practicing since :2007

Answered : 2407 Questions

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What Are The Withdrawal Symptoms Of Baclofen, Stablon And Stresnil?

Brief Answer: stop one by one under doctor's supervision Detailed Answer: Hello XXXXXXX Thanks for writing back to us. Stablon 12.5 mg is low dose. If he is better since more than 6 months in depression, stablon can be taken half (6.25 mg) for 20 days and then stopped. Baclofen as such is muscle relaxant. It can be decreased 10 mg every 15 days. Both of these drugs are not associated with withdrawals with slow tapering. Stressnil 0.5 mg contains alprazolam. It may be difficult to stop it suddenly. It should be continued until other two medicines completely stop. After than dose can be reduced to 0.25 mg for 1 month before stopping and simultaneously other measures for good sleep should be followed. I would recommend following 'sleep hygiene'. These are some measures called which would help in sleep. You can find the same in below link. sleepfoundation.org/ask-the-expert/sleep-hygiene Drinking a cup of warm milk before going to bed helps in 30-40% of patients and they do not need medicines as per my clinical experience. You can follow recommendations after discussing with his treating doctor. Hope I have answered your query, I will be happy to help further. Regards, Dr.Chintan Solanki.