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What Causes PVCs After Switching To A New Generic Drug?

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Posted on Mon, 3 Oct 2016
Question: Hello,
I have been having no issues for the past 1.5 years since being placed on Nadalol (generic Blue pill) for an AFIb occurance (only had 3 occurances within a 3 week timeframe in my life and was cardioverted. The last month the pharmacy switched my nadalol to another generic company (Yellow pill). I have noticed the past few days PVC's, not alot but I have to admit I had/have some anxiety anytime my heart has a hiccup. like I said the past 1.5years has been great with no known PVC's. My heart rate stays between 60-65 even when i experience this double beat then pause and back to normal. I had some old pills and started taking yesterday and the PVC's have almost gone away. Is it possible the generic pills are somehow a bit different. I also have been experiencing almost like butterflies the past 2 days. My one doctor feels I produce too much adrenaline and this is why nadalol works so much better than metatropol.

1-Can generic medicine be a bit different that could be causing this?
2-Is the butterflies adrenaline or am I getting some anxiety possibly
3-I also noticed this PVC is more active after I ate a big meal. (note:Cleveland Clinic Head of electrophysiology stated my Hiatal Hernia was pressing on Atrium causing rhythm disturbances and too eat small meals) I had a large amount of pizza yesterday and more than I have had in years (it was good) so this may be an issue. need to go back to small meals.
4-I gained a few pounds but still 15 pounds lighter than a year ago, was 323 now 307 and I am 6-4 tall
5_your input on what I should do thanks, I have always been in sinus rhythm since my cardioversion 3 years ago. The Cpap and Nadalol/Nexium has kept me in rhythm
doctor
Answered by Dr. Suresh Heijebu (10 hours later)
Brief Answer:
Nodalol /Nexium should be back

Detailed Answer:
Hello, Sir

I can certainly understand your concern.

I have worked through your query in detail.

Yes, change of medicine (generic name) can cause these symptoms.

Butterfly like Sensation could be due to associated anxiety.

PVC's can often get exaggerated following heavy meal.

This could be related to the underlying hiatal hernia .

Fatty meals like pizza can cause these symptoms.

Considering your recent symptoms, its important to reduce the bodyweight .

The hiatal hernia need a surgical correction.

It's important to get back to the generic Blue pill for effective control of symptoms.

Post your further queries if any.
Thank you.
Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar
doctor
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Follow up: Dr. Suresh Heijebu (5 hours later)
Thank you very much, I am having a PVC or PAC around 1 per minute or less right now. My heart rate is 60, should I seek medical advice?
doctor
Answered by Dr. Suresh Heijebu (16 hours later)
Brief Answer:
Advisable to see a cardiologist

Detailed Answer:
Hello, Sir.

Yes, you need to consult your cardiologist for further expert management.

A 24 hr Holster ECG can be helpful in these settings.

Post your further queries if any.
Thank you.
Note: For further queries related to coronary artery disease and prevention, click here.

Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar
doctor
Answered by
Dr.
Dr. Suresh Heijebu

Psychiatrist

Practicing since :2010

Answered : 3646 Questions

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What Causes PVCs After Switching To A New Generic Drug?

Brief Answer: Nodalol /Nexium should be back Detailed Answer: Hello, Sir I can certainly understand your concern. I have worked through your query in detail. Yes, change of medicine (generic name) can cause these symptoms. Butterfly like Sensation could be due to associated anxiety. PVC's can often get exaggerated following heavy meal. This could be related to the underlying hiatal hernia . Fatty meals like pizza can cause these symptoms. Considering your recent symptoms, its important to reduce the bodyweight . The hiatal hernia need a surgical correction. It's important to get back to the generic Blue pill for effective control of symptoms. Post your further queries if any. Thank you.