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What Causes A Level Of 10 G/L Of Serum Protein In Gamma Region?
Question: hello, I am 54 year male with very good health..can you please advise me in relation to paraprotein G Kàppa as per blood test..no one has raised it with however I want information on it as I have read that at 10g/l is is not a myloma and that this condition does not fight and infection...Can you give me your expert opinion..Is is a treatable condition does this mean that i will have difficulty fighting off the flue or a cold.
Brief Answer:
Level of 10 g/L not suggestive of plasma cell dyscrasia or low immunity.
Detailed Answer:
Hello,
Thanks for posting your query on HealthcareMagic.
The serum protein electrophoresis shows that there is increase in monoclonal proteins in gamma region.
However, a level of 10 g/L of serum protein in gamma region is insignificant.
The protein level becomes significant when level is above 35 g/L.
In addition, there is increase in alpha 1 and alpha 2 globulins which are acute phase reactants thus, there is a possibility that proteins in gamma region have increased in response to some acute infection or inflammation in body.
The immunity will not be affected or you will not become more prone to infections by increase in protein in gamma region so relax.
There is nothing to worry since the levels may come back to normal after the focus of infection / inflammation clears away from body.
To rule out the possibility of any plasma cell dyscrasia, you may get serum protein electrophoresis after a month.
Thanks and take care
Dr Shailja Puri
Level of 10 g/L not suggestive of plasma cell dyscrasia or low immunity.
Detailed Answer:
Hello,
Thanks for posting your query on HealthcareMagic.
The serum protein electrophoresis shows that there is increase in monoclonal proteins in gamma region.
However, a level of 10 g/L of serum protein in gamma region is insignificant.
The protein level becomes significant when level is above 35 g/L.
In addition, there is increase in alpha 1 and alpha 2 globulins which are acute phase reactants thus, there is a possibility that proteins in gamma region have increased in response to some acute infection or inflammation in body.
The immunity will not be affected or you will not become more prone to infections by increase in protein in gamma region so relax.
There is nothing to worry since the levels may come back to normal after the focus of infection / inflammation clears away from body.
To rule out the possibility of any plasma cell dyscrasia, you may get serum protein electrophoresis after a month.
Thanks and take care
Dr Shailja Puri
Note: Do you have more questions on diagnosis or treatment of blood disorders? Ask An Expert/ Specialist Now
Above answer was peer-reviewed by :
Dr. Vaishalee Punj
Answered by
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