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What Causes Elevated ALT And SGPT Levels?

Posted on Thu, 14 Jan 2016

Question: Hello Dr. I did BP, Pulse, Blood Sugar and Cholesterol and all reports are normal. However ALT/SGPT result is "59" while normal range is 20-49 and ESR result is '18' while normal range is 00-10. Would you please suggest if there are any concerns or do I have to start any medicines with immediate effect? Just FYI, I also uploaded the test reports to the portal for your review

Answered by Dr. Amit Jain (13 minutes later)

Brief Answer:
Take ursodeoxycholic acid and vitamin E

Detailed Answer:
Hello! Thanks for putting your query in HCM. I am a Gastroenterologist.

I have gone through the reports you have uploaded. I can understand your concerns.

Elevation of liver enzymes suggest liver cell injury. There are many cause like Hepatitis B, C, Metabolic disorders, NAFLD, alcohol intake, autoimmune disease etc. So I will suggest you to visit a Hepatologist or Gastroenterologist for evaluation who will advise tests and then manage accordingly.

Meanwhile there are few medicines which I found very useful in my patients are ursodeoxycholic acid and vitamin E. Ursodeoxycholic acid 300mg twice a day and Vitamin E capsule 400mg once a day. Both are available OTC.

Do regular exercise and reduce your weight if you are overweight, avoid alcohol if you drink.

I hope I have answered your query and this will help you . Wish you a good healthI hope I have answered your query and this will help you . Wish you a good health

Above answer was peer-reviewed by : Dr. Prasad

Follow up: Dr. Amit Jain (45 minutes later)

Thank You XXXXXXX for your wonderful suggestion. I will start the medicines you suggested above asap, so these medicines are based on ALT/SGPT and ESR reports right?

Just FYI, I don't drink alcohol but I do smoke often not sure if it's because of that?

Thanks again and have a great day ahead!

Answered by Dr. Amit Jain (18 hours later)

Brief Answer:
Ursodeoxycholic acid and Vitamin E are good for liver

Detailed Answer:
Welcome back. Sorry for delay

These medicines are hepatoprotective and prevent and improve liver cell injury and thus will help in bringing the levels down

Nice to hear that you dont drink alcohol as it is one most common cause of liver cell injury

Smoking does not lead to lead to elevation of liver enzymes

If you do not have any further query , you can close the discussion and rate the answer. Wish you a good health.

Above answer was peer-reviewed by : Dr. Sonia Raina