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What Causes Elevated BP Levels While On Midodrine?

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Posted on Wed, 25 Oct 2017
Question: my 86 year old wife has been taking 2.5 mg midodrine 3x daily to treat hydrostatic hypotension. She has been on it for about 2 weeks. I am now seeing a rise in BP laying down, sitting, or standing around 153 to 159 over 82 to 65. I believe we have over corrected and am inclined to either stop or reduce the midodrine. Would it be wise to do so?
doctor
Answered by Dr. Bhanu Partap (2 hours later)
Brief Answer:
Reducing the dose probably will help

Detailed Answer:
Hello Sir

After going through the medical history provided by you of your wife I would like to tell you that yes you are right and probably it's been getting over corrected.

So yes we can give it a try by reducing the frequency of the medicine to twice daily instead of thrice. Keeping monitoring her Bp for few days after reducing the medicine. Hopefully the Bp will come within normal range.

I hope this information will guide you properly

Kind Regards
Dr Bhanu Partap
Above answer was peer-reviewed by : Dr. Kampana
doctor
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Follow up: Dr. Bhanu Partap (16 hours later)
Thank you for your helpful response. A second question pertains to her new medication which is eliquis 2.5 mg which is to be taken twice daily to prevent stroke. She does have a kidney problem resulting from a heart attack and acute kidney failure 2 years ago. The kidneys have largely recovered to a creatine level of 1.62 where it has been stable over the past year or so. My main concern is will the new medication cause new damage to the kidneys and/or what to do to prevent damage. I look forward to your response.
doctor
Answered by Dr. Bhanu Partap (18 hours later)
Brief Answer

No significant effect on kidneys

Detailed Answer:
First of all my apologies for delayed response.

No sir it's fine to take the new medicine as it has no significant effect on kidneys.

To keep kidneys healthy just take water on regular 8 nt Ercall as it will help flush the toxins properly. Rest the medicines prescribed by nephrologist will take care no need to worry.

Hope to have been helpful.

Kind regards
Dr Bhanu partap
Note: For further queries related to coronary artery disease and prevention, click here.

Above answer was peer-reviewed by : Dr. Raju A.T
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Answered by
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Dr. Bhanu Partap

Cardiologist

Practicing since :2010

Answered : 4733 Questions

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What Causes Elevated BP Levels While On Midodrine?

Brief Answer: Reducing the dose probably will help Detailed Answer: Hello Sir After going through the medical history provided by you of your wife I would like to tell you that yes you are right and probably it's been getting over corrected. So yes we can give it a try by reducing the frequency of the medicine to twice daily instead of thrice. Keeping monitoring her Bp for few days after reducing the medicine. Hopefully the Bp will come within normal range. I hope this information will guide you properly Kind Regards Dr Bhanu Partap