Sign-in to Ask A Doctor - 24x7
OR
Sign in with Google
What Causes Elevated PSA?
Question: My husband's PSA number was 53 when checked this week. It has been going up, sometimes rapidly, for the last 10 years. He has had 4 biopsies and a rectal MRI. Nothing has been found to cause this. Now his doctor wants to do surgery to explore further. What could be causing his number to be going up and is surgery a good idea?
Brief Answer:
Raised PSA may be due to Enlarged Prostate .
Detailed Answer:
Hello
Thanks for your query ,based on the facts that you have posted it appears that your 70 years old husband has raising trend of PSA off and on for over last 10 years .have
I shall be happy if you can post me few more details to help me in making comments on your problem.
1) Does he have obstructing voiding symptoms like frequency ,poor stream ,urgency nocturia etc suggesting Enlarged prostate which is common at this age .?
2) What is volume of his prostate detected on Ultrasound Scanning and what is the post void urine residue ?
The commonest cause to raise PSA is either cancer of the prostate or acute infection of prostate (Prostatitis).As his repeated prostate biopsys have turned out to be negative for cancer of the prostate ,His raised PSA is mostly due to infection (Prostatitis).
Your Urologist has rightly advised him to get surgery done .Doing an endoscopic resection of prostate will help to
1) Confirm the diagnosis by submitting multiple chips of prostate tissue for biopsy
2) Eliminate the primary source for raised PSA .
3) To make him free of obstructive urinary symptoms source .
Hope I have answered your query ,please feel free to ask if you have more questions ,I shall be happy to help you
Thanks and Regards.
Dr.Patil
Raised PSA may be due to Enlarged Prostate .
Detailed Answer:
Hello
Thanks for your query ,based on the facts that you have posted it appears that your 70 years old husband has raising trend of PSA off and on for over last 10 years .have
I shall be happy if you can post me few more details to help me in making comments on your problem.
1) Does he have obstructing voiding symptoms like frequency ,poor stream ,urgency nocturia etc suggesting Enlarged prostate which is common at this age .?
2) What is volume of his prostate detected on Ultrasound Scanning and what is the post void urine residue ?
The commonest cause to raise PSA is either cancer of the prostate or acute infection of prostate (Prostatitis).As his repeated prostate biopsys have turned out to be negative for cancer of the prostate ,His raised PSA is mostly due to infection (Prostatitis).
Your Urologist has rightly advised him to get surgery done .Doing an endoscopic resection of prostate will help to
1) Confirm the diagnosis by submitting multiple chips of prostate tissue for biopsy
2) Eliminate the primary source for raised PSA .
3) To make him free of obstructive urinary symptoms source .
Hope I have answered your query ,please feel free to ask if you have more questions ,I shall be happy to help you
Thanks and Regards.
Dr.Patil
Note: Consult a Urologist online for consultation about prostate and bladder problems, sexual dysfunction, kidney stones, prostate enlargement, urinary incontinence, impotence and erectile dysfunction - Click here.
Above answer was peer-reviewed by :
Dr. Chakravarthy Mazumdar
Answered by
Get personalised answers from verified doctor in minutes across 80+ specialties
