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What Causes Elevated Liver Enzymes While On Celebrex?

Posted on Tue, 4 Aug 2015

Question: I have been taking Celebrex for many years now and I understand that my blood work shows that my liver count is getting close to the danger point, my doctor hasn't said anything, but I have learned that this is not good and I am not sure what to do about it

Answered by Dr. Kathy Robinson (47 minutes later)

Brief Answer:
not the Celebrex

Detailed Answer:
Hello,
Celebrex gets metabolized through the kidney not the liver so it should not be the problem. If your liver enzymes are elevated you need to be checked for hepatitis B and C and you may need a liver ultrasound.
You need to avoid all alcohol and acetaminophen.
Your doctor needs to take a close look at your medications and make sure you are not taking something like the statin drugs for cholesterol that can irritate the liver.
Drink plenty of water and get regular exercise like walking for 30 minutes a day.
Let me know if you have further questions.
Dr. Robinson

Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar

Follow up: Dr. Kathy Robinson (22 minutes later)

maybe I meant the Kidneys, so help please

Answered by Dr. Kathy Robinson (53 minutes later)

Brief Answer:
do you have bloodwork

Detailed Answer:
Hello,
It would help me to know what numbers you are talking about. Do you have any labwork that you could send me. Important liver enzymes would be AST, ALT, GGT, or alkaline phosphatase. Important kidney tests would be BUN, Creatinine or GFR.
If it is kidney function that is getting low then you would probably need to stop the celebrex.
Dr. Robinson

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Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar