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What Causes Heavy Menstrual Bleeding While On Acitrom?

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Posted on Fri, 3 Feb 2017
Question: I am suffering from Arteririal thromobosis & was operated in July 16 & 33 mm clot removed from left leg ankle Since then on Acitrome 5-6 mg & IT PNR conducted every fortnight

During the current mensus heavy bleeding for seven day with huge lumps

Also all dietry restriction like avoiding greeny leaf vegetable or other forms of vit k has been strictly observed during the last six months
doctor
Answered by Dr. Rini (57 minutes later)
Brief Answer:
Repeat PT/INR as soon as possible!

Detailed Answer:
Hi,
Thanks for choosing health care magic for your query!

Acitrome 5 to 6mg is quiet a high dose,and PT/INR should be repeated every 3rd day when you are on such high doses of acitrome.The degree of blood thinning is measured by a simple blood test called INR (International Normalised Ratio) or by PTT (Partial Prothrombin time).In your case target INR should be less then or equal to 2 ,INR if more then 2 can present with heavy bleeding and doses ;and should be tapered in that case for few days. It is very important to keep a record of all your acitrome doses and the blood test results in one place, such as a calendar,If you have one then please write down the date of test,the dose you were on and the PT/INR reading on that day. It will help me to review the pattern of acitrome doses and the blood test results over time and adjust the doses .
Healthy people who are not taking warfarin have an INR value of approximately 1.0. INR.In your case the INR should be between 2.0 and 3.0;but due to the history of heavy mensus ,i would like to keep it on the lower side(2).

Advice
1)Get you PT/INR checked as soon as possible,An INR greater than the target range ( you are over-anticoagulated) may put you at risk of serious bleeding, and is the most likely cause in your case.
2)Pt/Inr should be done every third day not every 14th day when you are on higher doses of anticoagulant.
3)Can ask your cardiologist to shift you on PRADAXA(dabigatran), they are nobel anti coagulants,and monitoring PT/INR is not required .They are equally effective in treating blood clots in the veins and arteries of your legs (deep vein thrombosis).Though only con associated with it is they are quiet costly.

In case you have any other query feel free to ask!

Thank you
Note: For further inquiries on surgery procedure and its risks or complications book an appointment now

Above answer was peer-reviewed by : Dr. Remy Koshy
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Answered by
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Dr. Rini

Cardiologist

Practicing since :2010

Answered : 140 Questions

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What Causes Heavy Menstrual Bleeding While On Acitrom?

Brief Answer: Repeat PT/INR as soon as possible! Detailed Answer: Hi, Thanks for choosing health care magic for your query! Acitrome 5 to 6mg is quiet a high dose,and PT/INR should be repeated every 3rd day when you are on such high doses of acitrome.The degree of blood thinning is measured by a simple blood test called INR (International Normalised Ratio) or by PTT (Partial Prothrombin time).In your case target INR should be less then or equal to 2 ,INR if more then 2 can present with heavy bleeding and doses ;and should be tapered in that case for few days. It is very important to keep a record of all your acitrome doses and the blood test results in one place, such as a calendar,If you have one then please write down the date of test,the dose you were on and the PT/INR reading on that day. It will help me to review the pattern of acitrome doses and the blood test results over time and adjust the doses . Healthy people who are not taking warfarin have an INR value of approximately 1.0. INR.In your case the INR should be between 2.0 and 3.0;but due to the history of heavy mensus ,i would like to keep it on the lower side(2). Advice 1)Get you PT/INR checked as soon as possible,An INR greater than the target range ( you are over-anticoagulated) may put you at risk of serious bleeding, and is the most likely cause in your case. 2)Pt/Inr should be done every third day not every 14th day when you are on higher doses of anticoagulant. 3)Can ask your cardiologist to shift you on PRADAXA(dabigatran), they are nobel anti coagulants,and monitoring PT/INR is not required .They are equally effective in treating blood clots in the veins and arteries of your legs (deep vein thrombosis).Though only con associated with it is they are quiet costly. In case you have any other query feel free to ask! Thank you