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What Causes High WBC Count And Negative HIV Result?

Posted on Sat, 6 Sep 2014

Question: Dear Dr.

I have been tested hiv p24/AB combo 4th gerenration 22 days after high risk exposure.

The test came up negtive

However, i have reactive Lymph nodes in different parts of my body,

I did CBC test

The result for wbc is 115000 (35000-11000 range)

Lymph was 45% (25 - 40%)

Do you think my test is conclusive?

What do u think about my high wbc??

Regards

Answered by Dr. Praveen G (1 hour later)

Brief Answer:
You are not having HIV.

Detailed Answer:
Hello,
Welcome to Healthcare Magic,

I have gone through your history and understand your concern about HIV. As your p24/AB combo test are negative after 22 days of possible exposure,You are not having HIV.

This tests can detect HIV virus as early as 10 days. This test will reduce the incubation period to less than 10 days.

As you have undergone CBC and the report are suggestive of some infection. Reactive lymph nodes mean lymph node is showing some infection. Biopsy of the lymph node will help us to know the other cause of lymph node enlargement

So you need not to worry about HIV infection, it may be some other infection I would suggest you to undergo lymph node biopsy to rule out the reason for lymph node enlargement.
Thank you.

Above answer was peer-reviewed by : Dr. Shanthi.E

Follow up: Dr. Praveen G (22 hours later)

Thank you sir for your answer

Does antibiotic have impact on the test result ??

Or on increasing the number of WBC?

I have been taking antibiotic for sore throat and mild fever and these medications are:

Schering - plough (AERIUS*5mg): Desloratading
Nexium (40mg tablet esomeprazile) AstraZeneca
Extra panadol
KLACID XL 500mg (7 tablets)
Strepsils

I have been taking them for 2 weeks

Thank you for you response in advance

Answered by Dr. Praveen G (2 hours later)

Brief Answer:
Antibiotic like control infection and reduce WBC

Detailed Answer:
Hello,
Welcome back to Healthcare Magic,

The aforementioned medications will help to control infection, fever and the soar throat. In fact antibiotics will control the infection and it will help to reduce the marginally raised WBC count.

Raised WBC count may be a sign of some infection, so antibiotic will help to bring down the raised WBC count.
Thank you.

Above answer was peer-reviewed by : Dr. Vinay Bhardwaj

Follow up: Dr. Praveen G (1 hour later)

Thank you doctor for information

Do you think these medications will impact my hiv test result and the vurial load in blood?
XXXXXXX test in 11 days?

P24 Ag rapid test in 11th and 19th day?

P24 Ag/ Ab combo in 19th and 22nd day after possible exposure?

Thank you again for yout kind response

Answered by Dr. Praveen G (29 minutes later)

Brief Answer:
No, These medicine has got no role on viral load

Detailed Answer:
Hello,
Welcome back to Healthcare Magic,

The aforementioned medications will help to control infection leading to fever and the soar throat and these medicines has got no role on the HIV viral load.

NAAT can detect virus in three days of infection.You are free of HIV.

P24 Combo test to detect P24 antigen of HIV as early as 10 days of possible exposure and detects antigen against HIV 1 and 2.

As it is non reactive it is conclusive that you are not having HIV infection. Just relax you are perfectly alright.
Thank you.

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Above answer was peer-reviewed by : Dr. Vinay Bhardwaj