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What Causes High Cholesterol Levels With Normal Angiogram?

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Posted on Wed, 7 Jan 2015
Question: Hi,
My father os 52 year old now and recently he had high blodd pressure in the range of 150-160/90-110. And then we met a cardiologist who prescribed lipid profile screening/ echo cardiogram/ ct-angiogram. I have attached the results. The doctor said the blood cholesterol is really high but angiogram seems normal. I request you to kindly go through the attached reports and provide your expert opinion.
doctor
Answered by Dr. Anantharamakrishnan (1 hour later)
Brief Answer:
Need more information

Detailed Answer:
Hi friend
Welcome to Health Care Magic

There are NO attachments! – technical issue? / Try again and attach. Alternatively you may send the reports to YYYY@YYYY with subject as "Attn: Dr. Anantharamakrishnan".

A normal angiogram is very much reassuring / it is the gold standard, against which others are compared.

He needs good control of pressure AND cholesterol
– what is the Lipid Profile report?
- What are his present medications?

Good luck
God bless you


Above answer was peer-reviewed by : Dr. Prasad
doctor
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Follow up: Dr. Anantharamakrishnan (33 minutes later)
Sir,I apologize for the inconvenience. I re attached them . Requesting you to check.
doctor
Answered by Dr. Anantharamakrishnan (23 minutes later)
Brief Answer:
Triglyceride needs attention

Detailed Answer:
Hi

Triglyceride is very high / level greater than 500 is called very high
A full 14-hour fasting is necessary for proper interpretation – did he fast properly?
Obesity / Diabetes / Thyroid insufficiency / Alcohol / over eating / some drugs like Beta-blockers, Diuretics are some causes.
It is generally genetic [inherited /running in family]

Eat fewer calories / Limit natural sugars:
Eat small, frequent meals and do not skip meals
Avoid late-night snacking
Add omega-3 fats in your diet
– fatty fish (like mackerel, salmon, sardines, tuna) twice or more in a week
– soy foods, canola oil, flax seeds and walnuts / limit potatoes, yams, beans, corn and peas
A good dietician can guide further... need to discuss a few times to grasp the subject well and follow it up

Lose weight if he is overweight

Do regular physical activity – at least half an hour a day / 5 days in a week

Because of such high level, drug should also be started simultaneously – usually in such situations a FIBRATE (Like fenofibrate or gemfibrosil) is started .
Cardiologist / Physician treating him will give appropriate prescription

Repeat the tests in 2 months

LDL is very good
HDL is a little low – not an issue now

Minor changes in ECHO are from pressure / heart function is good / Nothing to worry

Angiogram is normal / no clots / no narrowing / good

Regards

Above answer was peer-reviewed by : Dr. Prasad
doctor
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Follow up: Dr. Anantharamakrishnan (50 minutes later)
Hi doctor,
Thanks for the reply. No there was no instruction to fast. Would you recommend taking another test with 14 hr fast this time. And the doc prescribed below medication.
Zivast 10
Amlopres AT
Ecosprin 75

Do u think this is apt medication? If not would you recommend any other?
Thanks
doctor
Answered by Dr. Anantharamakrishnan (5 hours later)
Brief Answer:
Add a fibrtae

Detailed Answer:
Hi

Zivast is Atorvastatin / statins are good, but have more effects on cholesterol than Triglyceride(TG). Fibrates have better effects on TG. I will add a fibrate; for example change to something like Zivast-F that has both Atorvastatin and Fenofibrate

Repeat the test with 14-hour fast

Monitor the pressure; if the pressure isnot controlled in a week or more, the dose can be increased or a drug of the class ACEI (Angiotensin Enzyme Inhibitor) ARB (Angiotensin Receptor Blocker – like sartans) can be supplemented.

Regards
Note: For further queries related to coronary artery disease and prevention, click here.

Above answer was peer-reviewed by : Dr. Raju A.T
doctor
Answered by
Dr.
Dr. Anantharamakrishnan

Cardiologist

Practicing since :1966

Answered : 4505 Questions

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What Causes High Cholesterol Levels With Normal Angiogram?

Brief Answer: Need more information Detailed Answer: Hi friend Welcome to Health Care Magic There are NO attachments! – technical issue? / Try again and attach. Alternatively you may send the reports to YYYY@YYYY with subject as "Attn: Dr. Anantharamakrishnan". A normal angiogram is very much reassuring / it is the gold standard, against which others are compared. He needs good control of pressure AND cholesterol – what is the Lipid Profile report? - What are his present medications? Good luck God bless you