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What Causes Non-alcoholic Fatty Liver Disease?

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Posted on Wed, 22 Mar 2017
Question: I was recently diagnosed with non-alcoholic fatty liver disease. I see that some meds can cause this. I take for RA remicade infusion, sulfasalazine; pravastatin, warfarin for blood clots due to genetic px, fluoxetine, metformin. I am overweight (165 pounds/5"4") and aged 70. XXXXXXX
YYYY@YYYY


forgot to add that I am pre-diabetic. My father had diabetes.
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Answered by Dr. Dr. Ivan Romich (28 minutes later)
Brief Answer:
see next please

Detailed Answer:
Hi and welcome.

There are several factors which may contribute to nonalcoholic fatty liver and these are pre-diabetes and obesity which are most common risk factors. Medications may worsen the conditions as well, especially sulfaslazine and fluoxetine, but these are not the main cause.

To some degree, this is genetically determined, but you should reduce risk factors which are changeable so the first step is to control your body weight, blood sugar and blood lipids.

Also, if there's any history of alcohol and smoking, it must be avoided. Medication dosage can be reduced if necessary, but without lifestyle changes, there won't be much improvement.

It's a gradual process, and once implemented, improvements can be observed within a few months only.

Feel free to ask further.

Wish you good health.

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Above answer was peer-reviewed by : Dr. Arnab Banerjee
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Answered by
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Dr. Dr. Ivan Romich

General Surgeon

Practicing since :2008

Answered : 13888 Questions

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What Causes Non-alcoholic Fatty Liver Disease?

Brief Answer: see next please Detailed Answer: Hi and welcome. There are several factors which may contribute to nonalcoholic fatty liver and these are pre-diabetes and obesity which are most common risk factors. Medications may worsen the conditions as well, especially sulfaslazine and fluoxetine, but these are not the main cause. To some degree, this is genetically determined, but you should reduce risk factors which are changeable so the first step is to control your body weight, blood sugar and blood lipids. Also, if there's any history of alcohol and smoking, it must be avoided. Medication dosage can be reduced if necessary, but without lifestyle changes, there won't be much improvement. It's a gradual process, and once implemented, improvements can be observed within a few months only. Feel free to ask further. Wish you good health.