
What Causes Severe Fatigue?

He also has bouts of constipation and diarrhea; weekly.
Rule out the below mentioned diseases.
Detailed Answer:
Hello and thank you for asking on HCM!
Type 1 Diabetes is a disease that has autoimmune origin. It may be associated with other autoimmune diseases like under or overactive thyroid, adrenal gland insufficiency, anemia, celiac disease ect. If you didn't check for them I would recommend to do so;
-TSH, Ft4 and Ft3 to check the thyroid function
-Cortisol level to check the adrenal function
-Vit B12 level for anemia
-Anti- transglutaminase antibodies for celiac disease.
-Vit D level
Is the diabetes well controlled with insuline? How was the last HbA1c level?
High blood sugar may be manifested with the symptoms you mentioned. It is very important to maintain normal levels.
Regarding diarrhea , it may be caused from the damage of parasympathetic nerves from diabetes ( if he is diagnosed more than 5 years ago), celiac disease or Irritating bowel syndrome.
If all the above mentioned exams result normal, than depression may be the cause of fatigue and other symptoms.
Hope i have helped somewhat.
Kind regards,
Dr.Mirjeta

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