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What Do These Eosinophil And Lymphocyte Counts Indicate?

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Posted on Thu, 27 Oct 2016
Question: Hi Doctor, i need urgent help. My father's Eosinohil count is 34% and Lymphocytes is 8%. Can you help ke. He had recently undergone angioplasty and having skin irritations recently.
doctor
Answered by Dr. Panagiotis Zografakis (4 hours later)
Brief Answer:
please provide more info

Detailed Answer:
Hello,

I would need some more info to answer this question. First of all no test can be interpreted without clinical information. Why was the test done? Did he have any symptoms? What kind of skin irritations does he have? Do you have any recent blood counts for comparison? What about the rest of his medical history and drug use?

I've seen the blood count you've mentioned in another question. The lymphocytes are normal in absolute number. The neutrophils are borderline high and the eosinphils are sky high. If no reactive cause can be suspected then investigation for leukemia should be done. Anemia is not a good sign in this regard.

I'll be glad to continue this discussion when you provide more details.

Kind Regards!
Above answer was peer-reviewed by : Dr. Raju A.T
doctor
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Follow up: Dr. Panagiotis Zografakis (20 minutes later)
This is the report am having. He had an Angioplast during month of February. After that this skin irritations started. It was a regular blood test in which these counts came in. Also to note he had left ventricular heart failure last year after which this year this angioplasty was done. I do not have any reports with me now. Let me know if you need more details. Is high count of eosinophil predictive for blood cancer?
doctor
Answered by Dr. Panagiotis Zografakis (9 hours later)
Brief Answer:
I do need more...

Detailed Answer:
The answer is that I do need more information...
The eosinophils are usually elevated as a reaction to something. It could be due a parasitic infection, an allergic reaction, etc.
Rarer causes include autoimmune conditions and 'blood cancer'. Anything more than 1500 eosinophils (absolute number) raise suspicion for leukemia (what you've called blood cancer). This is by no means diagnostic though. The first thing your doctor should do is to try to exclude any potential cause of reactive elevation by:
- taking a detailed medical history, for example if he has any complaints, determine the nature of the skin lesions (for example an autoimmune condition called Churg-Strauss syndrome may cause skin lesions and an asthma like presentation with high eosinophil count in patients over 50 years with no history of asthma in the past), etc.
- do clinical examination which may provide useful clues like swollen lymph nodes or internal organs
- order appropriate tests (radiological tests - ultrasound and/or CT scans, specific tests for suspicious disorders, for example testing for anti-neutrophil-cytoplasmic antibodies - XXXXXXX - is essential for the diagnosis of Churg-Strauss syndrome).
- assess the rest of the tests he's already done.

So you understand that the details you've provided are not enough for a complete assessment. I can only describe the strategy of investigation with this information. Information like a full description of his complaints, a photo of the skin lesions (all of them) and any other relevant medical history would help. I'm not interested in his recent history only and the angioplasty (which could be irrelevant). I'm talking about the whole history and all the drugs he takes. A recently used drug for example may cause this disorder. It is useful to know when his last normal blood count was documented (a past report that is).

Kind Regards!
Note: For more detailed guidance, please consult an Internal Medicine Specialist, with your latest reports. Click here..

Above answer was peer-reviewed by : Dr. Nagamani Ng
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Answered by
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Dr. Panagiotis Zografakis

Internal Medicine Specialist

Practicing since :1999

Answered : 3815 Questions

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What Do These Eosinophil And Lymphocyte Counts Indicate?

Brief Answer: please provide more info Detailed Answer: Hello, I would need some more info to answer this question. First of all no test can be interpreted without clinical information. Why was the test done? Did he have any symptoms? What kind of skin irritations does he have? Do you have any recent blood counts for comparison? What about the rest of his medical history and drug use? I've seen the blood count you've mentioned in another question. The lymphocytes are normal in absolute number. The neutrophils are borderline high and the eosinphils are sky high. If no reactive cause can be suspected then investigation for leukemia should be done. Anemia is not a good sign in this regard. I'll be glad to continue this discussion when you provide more details. Kind Regards!