What Do These Following Lab Reports Indicate?
I am really worried. I have IVF pregnancy and now I am 12.4 weeks pregnant. As suggested by doctor I got my Dounle marker test done.pls refer the attacjed reports.
Its negative but above age risk.
My age : 27 years
My doctor has recomended 4d scan after 4 weeks that is when I will be 16 weeks pregnant.
Pls reply.
My readings are:
Free beta hcg: 135.00 ng/mL
Pappa: 1.53 mIU/mL
Corr. MOM's
Papp-A : 0.52
Free beta hcg - 2.98
Comments in report: In view of biochemical risk above age risk but below cut off risk 1:250, it is advisable to do higg level USG or confirmatory test under clinical guidance.
Also,
My Trisomy 21 is negative
Trisomy 13/18 is negative
But above age risk
Further readings: trisomy 21+ NT - risk is 1:514
Trisomy 13/18 - risk is 1: 1: 10000
Age risk : 1: 843
Pls reply.
No need to panic
Detailed Answer:
Hi dear,
I have gone through your question and understand your concerns.
I have reviewed the report.
The corrected MoM values of PAPP-A and beta hCG values are definitely deranged, however the calculated risk of chromosomal anomalies is low.
In this situation, nothing active needs to be done at this time.
However, a detailed anomaly ultrasound should be done at 18 weeks to rule out any major congenital anomalies.
You should get regular blood pressure check up as these markers can be deranged in hypertension of pregnancy also.
Hope you found the answer helpful.
Regards
Dr Deepti Verma
OBGYN
Maternal and fetal medicine specialist
My baby will not have any risk of down syndrome , right?
And will 4D scan help to rule out whether any problem is there or not???
Or ultrasound will help to rule out any problem at 16 weeks?
Also Doctor, can I do something to have all readings normal??
Hi doctor,
Can you pls reply for my above worries?
Nothing can be done to alter parameters
Detailed Answer:
Hi dear,
Yes, there is no risk of Down syndrome in your baby.
Nothing can be done to make the serum values normal.
You need not worry.
A 4 D ultrasound will detect any major congenital anomaly. It can be done anywhere between 16-20 weeks.
Regards
Dr Deepti Verma
I could not find normal ranges for both. Can you please tell me.
MoM cut offs
Detailed Answer:
Hi dear,
Your free beta hCG levels are high and PAPP-A levels are low. The reference values are the MoM cut off for both.
Regards
Dr Deepti Verma
Various problems
Detailed Answer:
Hi dear,
Deranged levels of hCG and PAPP-A can lead to growth restriction in baby, preterm labour, hypertension in pregnancy.
Your treating doctor will detect these conditions by appropriate examination and investigations.
Regards
Dr Deepti Verma
Happy to help
Detailed Answer:
Hi dear,
I am happy to have helped you.
You can get back to me anytime by asking a direct question to me on the healthcare magic portal.
Regards
Dr Deepti Verma
Thnks again!
Happy to help
Detailed Answer:
Hi dear,
Again, happy to help.
Regards
Dr D Verma
Answered by
Dr. Deepti Verma
OBGYN, Maternal and Fetal Medicine
Practicing since :2009
Answered : 5064 Questions