
What Does Abnormal Three Hour Glucose Test Indicate?

Pre diabetes
Detailed Answer:
There is a condition called pre diabetes that has specific diagnostic criteria just like there are clear cut offs for making a diagnosis of diabetes. The stabdard test for both thee conditions is called the 2 hour 75 gram Oral Glucose Tolerance test. This is perfirmed after an overnight fast of 8 to 14 hours. Drinking water is okay. The thresholds for diagnosis are as follows : fasting glucose value : 65 to 99 is Normal. 100 to 125 is called impaired fasting glucose. 126 or more is compatible with diabetes. Then 75 grams glucose is given with water and exactly at 2 hours a blood sample is taken. During this time one is supposed to be seated and none of the following is permitted : walking, smoking , eating, coffee etc. Only water is allowed. The cut offs at the 2 hour mark are as follows : less than 140 is normal. 140 to 199 is called Impaired glucose tolerance. 200 or more is considered to be diabetes. Now bear in mind that it is recommended that testing is repeated on a second occasion to be certain of the diagnosis. The whole glucose tolerance test need not be repeated. Either fasting or 2 hour post glucose can be done. There is a third screening blood test for diabetes called HbA1c. Even this can be used to make a diagnosis of diabetes versus pre diabetes. Less than 5.7% is normal. 5.7% to 6.4% is pre diabetes and 6.5% or more is tantamount to diabetes. The two terms above 'Impaired fasting glucose ' and ' Impaired glucose tolerance ' are also equivalent to diabetes. I don't see what your fasting glucose value is. I see you have mentioned that your 2 hour glucose reading was 150. If the test was performed using standard guidelines then your reading falls in the range of Pre diabetes


Follow up
Detailed Answer:
I am happy to note your successful professional life.
I am sorry to hear about the medical problems you are facing that have evaded a proper diagnosis thus far.
As alluded to above, based upon standard endocrine practice guidelines, you do not have diabetes nor pre diabetes. Pre diabetes does not have any specific symptoms. it is typically precursor to diabetes, as the name suggests but it can be present along with other metabolic conditions like high blood pressure, high cholesterol and overweight/obesity.
It appears you have had a thorough evaluation but just make sure the following tests have XXXXXXX done and are normal:
CBC
CMP
TSH FREE T4
25 HYDROXY VITAMIN D
Once it is clear that your hemoglobin,liver, kidney and electrolytes are normal then just have a documented blood test for thyroid (TSH, Free T4) and vitamin D. Insufficiency of either can produce symptoms similar to the ones you are experiencing

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