Sign-in to Ask A Doctor - 24x7
OR
Sign in with Google
What Does Estrogen Level Of 197 Indicate?
Question: hi ....i am on clomid 100 mg ( day 2-6 ) ...my oestrogen was 339 on day 8 , I had an ultrasound today , left ovary shows multiple follicle and right overy shows 2 follicle which is 10 mm each , blood test shows on day 12 the oestrogen level 197 , but my nurse says progesterone is going up . i am bit confused whats going on ?
Brief Answer:
looks like a suboptimal response
Detailed Answer:
Hello and welcome,
The estrogen levels show a wide range of variability in women.
However in most cases the estrogen levels increase steadily during the initial phase of the cycle and then after ovulation they drop a little bit. However your ultrasound and the hormone levels are not synchronous.
There was an initial rapid rise in estrogen but you do not show a dominant follicle in the ovary. Also please ask if there is a free fluid in the cul de sac as it indicates an ovulation that may have been missed on ultrasound [ happens rarely] as the progesterone levels are going up. Or another reason may be that the follicles have not yet developed enough [ may be a suboptimal response to clomid]. So please recheck the follicle status for the next few days.
As of now, there is not much that can be done in this cycle if there is no further growth of the follicles.
Please consult your gynecologist and discuss a fresh start for ovulation induction with either gonadotropins or clomid again after a break for a few months. Meanwhile if you have PCOD, diet control weight loss and exercise will help a lot.
All my good wishes are with you. Best of luck.
Hope this satisfies your query.
Thanks for using HCM.
Feel free to ask any more questions that you may have.
Dr Madhuri Bagde
Consultant Obstetrician and Gynecologist
looks like a suboptimal response
Detailed Answer:
Hello and welcome,
The estrogen levels show a wide range of variability in women.
However in most cases the estrogen levels increase steadily during the initial phase of the cycle and then after ovulation they drop a little bit. However your ultrasound and the hormone levels are not synchronous.
There was an initial rapid rise in estrogen but you do not show a dominant follicle in the ovary. Also please ask if there is a free fluid in the cul de sac as it indicates an ovulation that may have been missed on ultrasound [ happens rarely] as the progesterone levels are going up. Or another reason may be that the follicles have not yet developed enough [ may be a suboptimal response to clomid]. So please recheck the follicle status for the next few days.
As of now, there is not much that can be done in this cycle if there is no further growth of the follicles.
Please consult your gynecologist and discuss a fresh start for ovulation induction with either gonadotropins or clomid again after a break for a few months. Meanwhile if you have PCOD, diet control weight loss and exercise will help a lot.
All my good wishes are with you. Best of luck.
Hope this satisfies your query.
Thanks for using HCM.
Feel free to ask any more questions that you may have.
Dr Madhuri Bagde
Consultant Obstetrician and Gynecologist
Note: Revert back with your gynae reports to get a clear medical analysis by our expert Gynecologic Oncologist. Click here.
Above answer was peer-reviewed by :
Dr. Chakravarthy Mazumdar
Answered by
Get personalised answers from verified doctor in minutes across 80+ specialties
