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What Does My Biopsy Test Report Indicate?

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Posted on Wed, 5 Apr 2017
Question: My mother's spine biopsy report:
Crishind artifacts suggestive of round cell tumour, fibrocollagenous and adipose tissue paravertebral region biopsy
Definite granulomas or atypical cells are not seen.
Immunohistochemistry study is suggested for further confirmation and typing.

Please tell me what it means
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Answered by Dr. Ishu Bishnoi (8 hours later)
Brief Answer:
Round cell tumor

Detailed Answer:
Hi Npbala, thanks for asking from HCM.


I can understand your concern. Round cell tumor of thoracic vertebrae means any of these tumors like Ewing's sarcoma, peripheral neuroectodermal tumor, rhabdomyosarcoma, synovial sarcoma, non-Hodgkin's lymphoma.

These kind of tumor are usually chemotherapy and radiotherapy responsive. Prognosis will depend upon spread of tumor at the time of diagnosis. You should get her PET scan done to rule out any spread.

Surgery can be done if focal tumor. Complete surgical excision signifies good prognosis.

In cases of spine, common round cell tutors are either Ewing or Non-Hodgkin's lymphoma. You should consult neurosurgeon. He will guide you further.

If you have any doubt, do let me know.
Thanks. Take care.
Above answer was peer-reviewed by : Dr. Vaishalee Punj
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Answered by
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Dr. Ishu Bishnoi

Neurologist, Surgical

Practicing since :2007

Answered : 901 Questions

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What Does My Biopsy Test Report Indicate?

Brief Answer: Round cell tumor Detailed Answer: Hi Npbala, thanks for asking from HCM. I can understand your concern. Round cell tumor of thoracic vertebrae means any of these tumors like Ewing's sarcoma, peripheral neuroectodermal tumor, rhabdomyosarcoma, synovial sarcoma, non-Hodgkin's lymphoma. These kind of tumor are usually chemotherapy and radiotherapy responsive. Prognosis will depend upon spread of tumor at the time of diagnosis. You should get her PET scan done to rule out any spread. Surgery can be done if focal tumor. Complete surgical excision signifies good prognosis. In cases of spine, common round cell tutors are either Ewing or Non-Hodgkin's lymphoma. You should consult neurosurgeon. He will guide you further. If you have any doubt, do let me know. Thanks. Take care.