Question: In the past two years I have visited nearly every type of ologist, to get diagnosis. PCP is under the impression that i have fibromyalgia and chronic fatigue. I was referred to a rheumatologist who was not happy with that diagnosis because it left to much of my lab results and symptoms unaddressed. From the work ups that have currently been done they have pretty much ruled out autoimmune issues, lyme disease, IBS, neurological issues, and I don't have any markers for any type of arthritis. I have no family history of those types of diseases. I do have a family history of breast cancer, colon cancer, female cancers, leukemia, diabetes, heart disease, and kidney cancer.

I have been experiencing severe fatigue, nearly daily low grade fevers, bone pain, petechiae, paleness, flakey skin, full body muscle tension and weakness, muscle spasms, tenderness to touch, bone pain, re-occuring UTIs and bronchitis, night sweats, abdominal pain, poor appetite, poor sleep, major weight fluxations; and chronic direareha for about 8 years. My symptoms continue to get worse and I am sort of being treated for the fibro and narcolepsy. However, the current treatment is not really helping. Given the lab results posted below and several mentionings by physicains other than my PCP is seems that I have the beginnings of kidney disease. Looking at the remaining counts that are abnormal and one previous smudge cell that came back moderatetly abnormal, the last thing that truly has not been ruled out is a chronic leukemia. I feel that at this point a full year after these more severe sympoms developed that I am getting brushed off and I am wondering if I really need to seek a second opinion in haste. I am concerned about renal failure and the possibility of leukemia. What would you advise?

Chemistry

Na
137 mmol/L
Date: XXXXXXX 14, 2016 04:51 p.m. EST Reference Range:137 mmol/L - 145 mmol/L
K
3.2 mmol/L (Low)
Date: XXXXXXX 14, 2016 04:51 p.m. EST Reference Range:3.5 mmol/L - 5.1 mmol/L
Cl-
99 mmol/L
Date: XXXXXXX 14, 2016 04:51 p.m. EST Reference Range:96 mmol/L - 107 mmol/L
HCO3
26 mmol/L
Date: XXXXXXX 14, 2016 04:51 p.m. EST Reference Range:22 mmol/L - 30 mmol/L
Anion Gap
12 mmol/L
Date: XXXXXXX 14, 2016 04:51 p.m. EST Reference Range:5 mmol/L - 14 mmol/L
BUN
18 mg/dL
Date: XXXXXXX 14, 2016 04:51 p.m. EST Reference Range:7 mg/dL - 20 mg/dL
Cret
1.05 mg/dL (High)
Date: XXXXXXX 14, 2016 04:51 p.m. EST Reference Range:0.60 mg/dL - 1.00 mg/dL
Estimated GFR, Black Race
> 60 mL/min/1.73 m2
Date: XXXXXXX 14, 2016 04:51 p.m. EST Reference Range:> 60 mL/min/1.73 m2
Estimated GFR, non-Black Race
59 mL/min/1.73 m2 (Low)
Date: XXXXXXX 14, 2016 04:51 p.m. EST Reference Range:> 60 mL/min/1.73 m2
Glu
144 mg/dL (High)
Date: XXXXXXX 14, 2016 04:51 p.m. EST Reference Range:74 mg/dL - 106 mg/dL
Ca
9.5 mg/dL
Date: XXXXXXX 14, 2016 04:51 p.m. EST Reference Range:8.4 mg/dL - 10.2 mg/dL
CBC

WBC
10.65 K/uL (High)
Date: XXXXXXX 14, 2016 04:51 p.m. EST Reference Range:4.0 K/uL - 10.4 K/uL
Hgb
13.2 g/dL
Date: XXXXXXX 14, 2016 04:51 p.m. EST Reference Range:11.7 g/dL - 15.0 g/dL
Hct
40.5 %
Date: XXXXXXX 14, 2016 04:51 p.m. EST Reference Range:35 % - 44 %
RBC
4.68 M/uL
Date: XXXXXXX 14, 2016 04:51 p.m. EST Reference Range:3.90 M/uL - 5.00 M/uL
MCV
86.5 fL
Date: XXXXXXX 14, 2016 04:51 p.m. EST Reference Range:81 fL - 96 fL
MCHC
32.6 g/dL
Date: XXXXXXX 14, 2016 04:51 p.m. EST Reference Range:32 g/dL - 36 g/dL
MCH
28.2 pg
Date: XXXXXXX 14, 2016 04:51 p.m. EST Reference Range:28 pg - 33 pg
RDW
13.6 %
Date: XXXXXXX 14, 2016 04:51 p.m. EST Reference Range:11.5 % - 14.2 %
Plts
393 K/uL (High)
Date: XXXXXXX 14, 2016 04:51 p.m. EST Reference Range:150 K/uL - 350 K/uL
MPV
11.4 fL
Date: XXXXXXX 14, 2016 04:51 p.m. EST Reference Range:9.0 fL - 12.2 fL
Type of Diff:
AUTO
Date: XXXXXXX 14, 2016 04:51 p.m. EST
Immature Gran%
0.2 %
Date: XXXXXXX 14, 2016 04:51 p.m. EST
Neut%
46.9 %
Date: XXXXXXX 14, 2016 04:51 p.m. EST
Lymph%
41.6 %
Date: XXXXXXX 14, 2016 04:51 p.m. EST
Mono%
7.9 %
Date: XXXXXXX 14, 2016 04:51 p.m. EST
Baso%
0.5 %
Date: XXXXXXX 14, 2016 04:51 p.m. EST
Eos%
2.9 %
Date: XXXXXXX 14, 2016 04:51 p.m. EST
Immat Gran, Abs
0.02 K/uL
Date: XXXXXXX 14, 2016 04:51 p.m. EST Reference Range:0 K/uL - 0.4 K/uL
Neut, Abs
5.00 K/uL
Date: XXXXXXX 14, 2016 04:51 p.m. EST Reference Range:2.0 K/uL - 7.7 K/uL
Lymph, Abs
4.43 K/uL (High)
Date: XXXXXXX 14, 2016 04:51 p.m. EST Reference Range:1.0 K/uL - 3.4 K/uL
Mono, Abs
0.84 K/uL
Date: XXXXXXX 14, 2016 04:51 p.m. EST Reference Range:0 K/uL - 1.0 K/uL
Baso, Abs
0.05 K/uL
Date: XXXXXXX 14, 2016 04:51 p.m. EST Reference Range:0 K/uL - 0.1 K/uL
Eos, Abs
0.31 K/uL
Date: XXXXXXX 14, 2016 04:51 p.m. EST Reference Range:0 K/uL - 0.5 K/uL
Liver/GI

ALT
25 unit/L
Date: XXXXXXX 14, 2016 04:51 p.m. EST Reference Range:13 unit/L - 69 unit/L
T Bili
0.4 mg/dL
Date: XXXXXXX 14, 2016 04:51 p.m. EST Reference Range:0.2 mg/dL - 1.3 mg/dL
Alk Phos
99 unit/L
Date: XXXXXXX 14, 2016 04:51 p.m. EST Reference Range:38 unit/L - 126 unit/L
AST
32 unit/L
Date: XXXXXXX 14, 2016 04:51 p.m. EST Reference Range:15 unit/L - 46 unit/L
Nutrition

Alb
4.4 g/dL
Date: XXXXXXX 14, 2016 04:51 p.m. EST Reference Range:3.5 g/dL - 5.0 g/dL
Prot
7.8 g/dL
Date: XXXXXXX 14, 2016 04:51 p.m. EST Reference Range:6.3 g/dL - 8.2 g/dL
Vitamin D, 25-Hydroxy
20 ng/mL (Low)
Date: XXXXXXX 14, 2016 04:51 p.m. EST Reference Range:30 ng/mL - 100 ng/mL
Cardiac/Lipi

CPK
106 unit/L
Date: XXXXXXX 14, 2016 04:51 p.m. EST Reference Range:30 unit/L - 135 unit/L
Endocrine

TSH
1.28 uIU/mL
Date: XXXXXXX 14, 2016 04:51 p.m. EST Reference Range:0.47 uIU/mL - 4.68 uIU/mL
T4
10.2 ug/dL
Date: XXXXXXX 14, 2016 04:51 p.m. EST Reference Range:5.5 ug/dL - 11.0 ug/dL
Rheumatology

RF
< 9 I.U./mL
Date: XXXXXXX 14, 2016 04:51 p.m. EST Reference Range:< 12 I.U./mL
CCP Ab
0.5 unit/mL
Date: XXXXXXX 14, 2016 04:51 p.m. EST Reference Range:< 5.0 unit/mL
ANA Ab, by IFA
<1:40
Date: XXXXXXX 14, 2016 04:51 p.m. EST
ANA Ab, Hold for Component Ag
No further testing needed, ANA Ab, by IFA is Negative.
Date: XXXXXXX 14, 2016 04:51 p.m. EST
SSA Antibody
22 AU/mL
Date: XXXXXXX 14, 2016 04:51 p.m. EST Reference Range:< 100 AU/mL
SSB Antibody
34 AU/mL
Date: XXXXXXX 14, 2016 04:51 p.m. EST Reference Range:< 100 AU/mL
Anti Proteinase Ab
< 1.0
Date: XXXXXXX 14, 2016 04:51 p.m. EST XXXXXXX Screen
Negative
Date: XXXXXXX 14, 2016 04:51 p.m. EST
ANA Comment
DNR
Date: XXXXXXX 14, 2016 04:51 p.m. EST
tTG-IgA Ab
1
Date: XXXXXXX 14, 2016 04:51 p.m. EST
tTG-IgG Ab
3
Date: XXXXXXX 14, 2016 04:51 p.m. EST
CReacProt
2.22 mg/dL (High)
Date: XXXXXXX 14, 2016 04:51 p.m. EST Reference Range:< 1.00 mg/dL
AntiMyeloperxds
< 1.0
Date: XXXXXXX 14, 2016 04:51 p.m. EST
ESR
36 mm/hr (High)
Date: XXXXXXX 14, 2016 04:51 p.m. EST Reference Range:0 mm/hr - 20 mm/hr
UricAcid
10.8 mg/dL (High)
Date: XXXXXXX 14, 2016 04:51 p.m. EST Reference Range:2.5 mg/dL - 6.2 mg/dL
Heme/Onc

B12
340 pg/mL
Date: XXXXXXX 14, 2016 04:51 p.m. EST Reference Range:200 pg/mL - 900 pg/mL
Folate
7.8 ng/mL
Date: XXXXXXX 14, 2016 04:51 p.m. EST Reference Range:4.2 ng/mL - 20.0 ng/mL
Immunology

Prot, Serum
7.6 g/dL
Date: XXXXXXX 14, 2016 04:51 p.m. EST Reference Range:6.0 g/dL - 7.8 g/dL
Lyme Antibodies, IgG/IgM
NEGATIVE
Date: XXXXXXX 14, 2016 04:50 p.m. EST Reference Range:NEG
Lyme IgG Antibodies
Patient is negative for Lyme antibody. No further testing indicated.
Date: XXXXXXX 14, 2016 04:51 p.m. EST
Lyme IgM Antibodies
Patient is negative for Lyme antibody. No further testing indicated.
Date: XXXXXXX 14, 2016 04:51 p.m. EST
Lyme Antibodies Comment
Patient is negative for Lyme antibody. No further testing indicated.
Date: XXXXXXX 14, 2016 04:51 p.m. EST
S cerevisiae IgA
9.1
Date: XXXXXXX 14, 2016 04:51 p.m. EST
S cerevisiae IgG
8.5
Date: XXXXXXX 14, 2016 04:51 p.m. EST
Urine

Color (u)
YELLOW
Date: XXXXXXX 14, 2016 05:04 p.m. EST
Appear (u)
CLEAR
Date: XXXXXXX 14, 2016 05:04 p.m. EST
Glu (u)
NEGATIVE mg/dL
Date: XXXXXXX 14, 2016 05:04 p.m. EST Reference Range:NEG
Bili (u)
NEGATIVE
Date: XXXXXXX 14, 2016 05:04 p.m. EST Reference Range:NEG
Ketones
NEGATIVE mg/dL
Date: XXXXXXX 14, 2016 05:04 p.m. EST Reference Range:NEG
SG
1.015
Date: XXXXXXX 14, 2016 05:04 p.m. EST
Hgb (u)
NEGATIVE
Date: XXXXXXX 14, 2016 05:04 p.m. EST Reference Range:NEG
pH (u)
6.0 unit
Date: XXXXXXX 14, 2016 05:04 p.m. EST Reference Range:4.5 unit - 8.0 unit
Prot (u)
NEGATIVE mg/dL
Date: XXXXXXX 14, 2016 05:04 p.m. EST Reference Range:NEG
Urobili
0.2 EU/dL
Date: XXXXXXX 14, 2016 05:04 p.m. EST Reference Range:0.1 EU/dL - 1.0 EU/dL
Nitrite (u)
NEGATIVE
Date: XXXXXXX 14, 2016 05:04 p.m. EST Reference Range:NEG
Leuk Est
NEGATIVE
Date: XXXXXXX 14, 2016 05:04 p.m. EST Reference Range:NEG
WBC (u)
5-9 /HPF
Date: XXXXXXX 14, 2016 05:04 p.m. EST Reference Range:0 /HPF - 4 /HPF
RBC (u)
0-4 /HPF
Date: XXXXXXX 14, 2016 05:04 p.m. EST Reference Range:0 /HPF - 4 /HPF
Bact (u)
MODERATE (Abnormal)
Date: XXXXXXX 14, 2016 05:04 p.m. EST Reference Range:NONE
Blood Bank

HLA B27
B27 ANTIGEN IS NOT PRESENT
Date: XXXXXXX 14, 2016 04:51 p.m. EST

From what I understand the labs would suggest kidney disease in its early phases. renal failure is prevalent in my family from age 50 up. As I had many issues as a child due partially from my premature birth. is this something my pcp should be addressing?

The lab results showing high platelets, high ESR and high lymphocytes has been consistently for over a year. Does a diagnosis of Fibromyalgia support such results or should I seek another opinion?