Question: I have no symptoms-routine blood work platelets low 133 thou/mcl, MPV high 10.6 , my physical was just rescheduled and it was fact that MD office called me that I looked at my labs. I work in hospital as a PT so I have some knowledge. Usually I would expect these to both be high or low I am now rescheduled for march 10-should I go see hematologist or are these minor variances-maybe just recheck

What about DITP my theory-during period of sinus infection took zantac-maybe every 2-3 days due to increased stomach irritation-I usually take 3x per month or so. But I know that I took about 1 week or so, maybe even as cloase as 2 days before my blood test as I remember a night where I had some lemonade too close to bed time and was getting a little reflux from it and I think that night was 2-3 nights before my blood test. I looked up in a data base and saw that in case studies, Zantac has been linked to DITP-would that possibly cause the small thrombocytopenia we see and rise in MPV- you mentioned that there could be other subtle causes-any thing else for me to think of?

to make last query a little clearer- I took zantac during sinus infection more regularly-but only maybe 2 or 3 times in the two weeks leading up to the blood test. The reason I mention was that I was taking more regularly than almost any other time in my life-I have usually only used Tums for occasional heart burn-maybe I buy one container per year. Zantac seemed to work even better, but I had only started trying this 6 months ago and I bought my second box during sinus infection. I say all this to suggest-I had almost no experience with Zantac prior to 6 months ago. I suddenly ramp up. Maybe this is why I never had thrombocytopenia and now I gave my immune system a decent dose of it while it was already amped up fighting my sinus infection? The reason why I mention that I only took a few times before blood test was-maybe that is why the number is a smaller bump in MPV and thrombocytopenia and the variance would have been larger if I had been tested a few weeks earlier?

Just re-read your original response-I did seek an order to retest and will again late February. In relation to above-I am not taking Zantac any longer and have not needed to since blood test as part of my above theory. Hoping everything normalizes!

Would you advise that I hold on the Ranitidine for now? Or take when needed? (As I mentioned before, I usually only take 1-2x per month) I am having one of the days where I could use it.... Lets say I do hold Ranitidine-my next CBC is normal-would it make sense/ be advised that I schedule another one 1 month or so later-and take some Ranitidine with some frequency leading up to it. Interesting, only 30 cases...I get the impression that you think that my theory is unlikely/DITP would be rare in my case. Maybe I seized upon that as a possibility as the other causes of thrombocytopenia are kind of grave and I am not really showing any symptoms (that I can see) It sounds like I have to hope that everything just normalizes- thank you