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What Is An Idiosyncratic Reaction?

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Posted on Fri, 1 Jul 2016
Question: i took a first dose of gabepentin 300 mg my blood pressure was180 over99 i felt stupidly drunk spinning dizzy irritable just nervous off balance etc the list goes on they callled it an idiosynchratic reaction what does that mean and it was also taken with my normal medications it was prescribed for a migraine they had been treating for three weeks whats your opinion worst experience ever
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Answered by Dr. Dr. Chintan Solanki (44 minutes later)
Brief Answer:
it is hypersensitivity

Detailed Answer:
Hello XXXXXXX

Thanks for writing to us. I can understand your concern.

What you have suffered after taking first dose of gabapentin is called idiosyncratic reaction to drug. In simple words it is hypersensitivity to drug. Any individual can suffer from such type of reaction to any drug. Whenever an individual takes any drug for the first time he/she may suffer from such abnormal reaction and there are no predictive factors. Better to avoid that drug again.

Other possibility is drug interaction. You have taken gabapentin with other drugs fro migraine. There can be drug interaction between gabapentin and the drugs you have taken with it. Please let me know which drugs have you taken with gabapentin (or with maximum 4 hours of gap) for comments on possibility of drug interaction.

Hope I have answered your query, I will be happy to help further.

Regards,

Dr.Chintan Solanki.
Note: For further guidance on mental health, Click here.
Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar
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Answered by
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Dr. Dr. Chintan Solanki

Psychiatrist

Practicing since :2007

Answered : 2407 Questions

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What Is An Idiosyncratic Reaction?

Brief Answer: it is hypersensitivity Detailed Answer: Hello XXXXXXX Thanks for writing to us. I can understand your concern. What you have suffered after taking first dose of gabapentin is called idiosyncratic reaction to drug. In simple words it is hypersensitivity to drug. Any individual can suffer from such type of reaction to any drug. Whenever an individual takes any drug for the first time he/she may suffer from such abnormal reaction and there are no predictive factors. Better to avoid that drug again. Other possibility is drug interaction. You have taken gabapentin with other drugs fro migraine. There can be drug interaction between gabapentin and the drugs you have taken with it. Please let me know which drugs have you taken with gabapentin (or with maximum 4 hours of gap) for comments on possibility of drug interaction. Hope I have answered your query, I will be happy to help further. Regards, Dr.Chintan Solanki.