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What Is The Treatment For Uncontrolled Hypertension?

Posted on Tue, 21 Jan 2014

Question: hi I am 50yrs. Presently I am suffering with uncontrolled hypertension. My present medication is: aldomet 500mg twice a day, lisinopril 10mg twice a day and atenonol 50mg once a day. I have tried nefedipine and feldopine before but these while lowering the pressure causes the pulse to be high [ more than 100] . I have been hospitalised twice recently with this problem. Liver and kidney function is good. Also cholesterol level is good. An echocardiogram of the heart has shown very mild hypertrophy septum as well as very mildly dilated left atrium. Estimated ejection fraction 60%. present BP range 130-150/ 85-103. Pressure increases from mid afternoon and is peak at nightime. Could advise on medication that can assists.

Answered by Dr. Anantharamakrishnan (43 minutes later)

Brief Answer: Another drug / dose adjustment Detailed Answer: Hi, Welcome to Health Care Magic Echocardiogram is reasonable Normal Liver, Kidney and Cholesterol are reassuring Hypertension appears to be resistant Drugs and doses have to be tailored to the individual Adding a diuretic – like Chlorthalidone or Hydrochlorothiazide (12.5 mg) – can help. Also, Lisinopril can be increased – the dose is up to 40 mg Good luck Take care Wishing all well God bless

Above answer was peer-reviewed by : Dr. Raju A.T

Follow up: Dr. Anantharamakrishnan (2 hours later)

Hi thanks or your quick response. Based on your answer am i to take as follows: Aldomet 500mg and lisinopril 20mg twice daily Hydrochlorothiazide 12.5mg in the morning Atenonol 50mg once a day What could be causing the pressure to rise at night time? Also I find atenonol as being as minimal effect on the pressure except for reducing the pulse rate. Look forward to your response

Answered by Dr. Anantharamakrishnan (1 hour later)

Brief Answer: Yes Detailed Answer: Hi It is difficult to say why there is a rise at night / it is far easier to treat than to find the cause in many areas of Medicine / The process is long, cumbersome and not cost efficient. The most common cause is the kidney and it is reassuring to know the function is normal. Condition like Pheochromocytoma (adrenaline secreting) need to be evaluated.. The maximum dose of atenolol is 100 mg / if it has no effect and the rate is slowed down, you can try to withdraw it. Beta-blocker should NOT be stopped suddenly - you can half the dose first and observe. Take atenolol it in the evening / Take thiazide in the morning / when things are stable, you can plan to modify the doses, drugs or timings... You MUST be in touch with your doctor / he should be aware / will give appropriate prescription / and follow up... Regards

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Above answer was peer-reviewed by : Dr. Prasad