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When Do Liver Metastases Cause Liver Failure In A Person With Metastatic Colon Cancer?

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Posted on Fri, 8 May 2015
Question: When do liver mets cause liver failure in metastic colon cancer ?
doctor
Answered by Dr. Dr.Albana Sejdini (1 hour later)
Brief Answer:
On late stage of colon cancer....

Detailed Answer:
Hi XXXX,

Liver failure is caused when liver mets occupy the majority part of liver, on late stage of the primary disease (colon cancer).
Let me know if you need further information!
Dr.Albana
Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar
doctor
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Follow up: Dr. Dr.Albana Sejdini (25 minutes later)
My dad knw stage 4 cc and has around 9/10 liver mets but liver funtion tests was still ok so I was wondering ?
doctor
Answered by Dr. Dr.Albana Sejdini (3 hours later)
Brief Answer:
Following explanation. ...

Detailed Answer:
Hi back,

I am sorry for the situation your father is in. May God alleviate his sufferings.

Although mets have occupied 9/10 of his liver, it will depend on response of liver. If its function evaluated by liver function test showed normal/acceptable levels, it means that liver is not completely damaged.

Please bare in mind that liver is an extraordinary organ with special characteristics of continuous regeneration.
At what point it will keep regenerating, no doctor can predict.

All the best and God bless !
Dr.Albana
Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar
doctor
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Follow up: Dr. Dr.Albana Sejdini (3 hours later)
Ok .

At present his liver function tests seem normal which I was surprised .

But these can change right ?

Also he's had 1 round of chemo -oxyplatin and cea jumped from 65 to 78 in 3 weeks after first treatment . It was 65 three days before chemo started

Does this mean not working ?
doctor
Answered by Dr. Dr.Albana Sejdini (14 hours later)
Brief Answer:
Liver function can change(nobody can tell when&how);CEA not for follow up..

Detailed Answer:
Hi,

Yes, you are right, liver function can change. However, no body can predict the time this is happening neither if it will be changed for worst or remain as good as now.

With regards to CEA level, it is not taken into account when it comes to follow up in colon cancer patients neither in evaluating the success of chemo. There are other factors to consider to evaluate the success of chemotherapy.

All the best!
Dr.Albana
Note: For further follow up on related General & Family Physician Click here.

Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar
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Answered by
Dr.
Dr. Dr.Albana Sejdini

General & Family Physician

Practicing since :2006

Answered : 7309 Questions

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When Do Liver Metastases Cause Liver Failure In A Person With Metastatic Colon Cancer?

Brief Answer: On late stage of colon cancer.... Detailed Answer: Hi XXXX, Liver failure is caused when liver mets occupy the majority part of liver, on late stage of the primary disease (colon cancer). Let me know if you need further information! Dr.Albana