Question: Yes Which hospital is best for the treatment of Multiple Myeloma? I have IgG Kappa light chains. Serum IgG immunogobulins of about 2800. No Bence XXXXXXX in Urine. Beta 2 is about 2.8. Below normal red blood cell count. Hemoglobin at low point of normal. I have a lot of leg pain below the knee which is relatively new for me. I can't tell if it is the bone, nerves, or muscle causing pain. Diagnosed with MGUS in 2009. Older brother diagnosed with multiple myeloma in 2011. Paternal grandmother had leukemia and maternal uncle did too. At what number of IgG immunogobulins will be considered high enough for multiple myeloma. How high does Beta 2 have to be? I had to have my parathyroids removed and I take calcium supplements and D3 so I do not know if calcium levels will show accurate destruction of bones. I also have a goiter with a couple of growths on my thyroid that are being checked every 3 years. I have hypothyroiditis. My lymph nodes in chest are enlarged but benign. I have had a fundic gland growth removed from my stomach two years ago and will be going back soon to have a second one removed if possible. Lucky me. I have cardiomyopathy with congestive heart failure, acid reflux, IBS, high blood pressure, sleep apnea which is untreated, ect. I have thought about going to Mayo Clinic and letting the doctors there put their heads together and see what they come up with. I am a 60 year old white woman. I have had joint pain for many years and have degenerative back disease. I am overweight. It is hard to exercise with joint pain. I just had a bi-ventricular pacemaker replaced and I am in a weakened state because a lead to my pacemaker has been breaking down over the last two years. A new lead was put in. I guess I am just scared. My hematologist says I will not die from multiple myeloma. My heart will kill me. My cardiologist says I will live another 20 years. Are these doctors just blowing smoke to keep me from worrying? I have not been the luckiest person in the world! Let me just add that I have been having fainting spells off and on since the age of 14. Sometimes I loose consciousness and sometimes I don't. When it is bad, I fall a lot. Six falls last year. None so far this year. MRI on brain 20 years ago just showed chronic sinus disease. No doctor has been able to identify the cause for the fainting spells. I have also lost over half my hair on my head and all the hair under my arms over the last few years. My added weight seems to be mostly in my neck and trunk.