Which Genetic Test Predicts How Effective Psychiatric Medication Are At Decreasing Future Psychosis?

Posted on Wed, 18 Nov 2015

Medically reviewed by Ask A Doctor - 24x7 Medical Review Team

Wed, 18 Nov 2015 Answered on

Tue, 15 Dec 2015 Last reviewed on

Question : Hi Dr Sheppe,
What kind of genetic analysis should I get?
This is XXXXXXX XXXX feeling trapped by bipolar depression .

There's: CYP450, CYP2D6, CYP2C19, CYP1A2 or NAT2

What's the best time for you? I'm on CST
I feel confused as to how I become your patient when I am being sent to this same page again

Answered by Dr. Alexander H. Sheppe (4 hours later)

Brief Answer:
Consultation

Detailed Answer:
Hello XXXXXXX

Thanks for your direct premium question. I've answered your other query regarding how we can do direct therapy together on your other thread. I'm on EST, by the way, as I live in NYC. For your question about genetic testing,let me give you my personal recommendation that I use with my patients.

The most popular and reliable genetic test available for psychiatric medications is GeneSight. I should mention that I have no financial connection to this company whatsoever -- it is simply the best and I and all my colleagues use it. The website is here:

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Here is an article discussing it:

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This test is often covered by insurance companies. I would check with GeneSight customer representatives as well as your doctor and insurance to figure out how much you can get covered. It is very expensive without insurance (about $3500), so make sure to try and get it covered. This test covers all CYP enzymes and many others.

Dr. Sheppe

Above answer was peer-reviewed by : Dr. Arnab Banerjee