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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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Advised To Take Lonazep With Qutan. Diagnosed With FTLD. Increased Agitation And Violence When Reduced Dosage? Continue Medications?

my wife ( 56 yrs)has been advised last june (2012 ) to take lonazep .5 and .25 in a day with qutan .25 and .5 for agitation and sizures . she has been diagnosed with FTLD with some psychiatric manifestation . her condition worsened over 8/9 months gradually .. sphincter control completely affected with incontinence for last two months . lonazep was increased to 2 mg in a day and now reduced again to 1 mg and asked to reduce further by .125 every fortnight .Her agitation and violence was very high when we started reducing lonazep .

Should we continue such medication for a patient who is rather suffering from dementia than any other type ?

PKM
Wed, 24 Apr 2013
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Internal Medicine Specialist 's  Response
hi
Frontotemporal lobar degeneration (FTLD) is the name for a group of clinically, pathologically and genetically heterogeneous disorders associated with atrophy in the frontal lobe and temporal lobe of the brain, with sparing of the parietal and occipital lobes.
In the over 65 age group, FTLD is probably the fourth most common cause of dementia after Alzheimer's disease, dementia with Lewy bodies and vascular dementia. In the below 65 age group, it is the second most common cause after Alzheimer's disease. In some patients the symptoms of FTLD and Alzheimer's may overlap

so what your was surffering either of the two
1 fast withdrawal of lonzep ...with withdrawal symptoms with anger and more agitation or
2 neuroleptic malignant syndrome from qutan
more fast dementia means more urinary incontinence.....such medications are sometimes important and sometimes are totally useless....it just weighing of the benefits or side effects or medcinies that you have to decide.....what is better for her wit or with out medicine
take care
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Advised To Take Lonazep With Qutan. Diagnosed With FTLD. Increased Agitation And Violence When Reduced Dosage? Continue Medications?

hi Frontotemporal lobar degeneration (FTLD) is the name for a group of clinically, pathologically and genetically heterogeneous disorders associated with atrophy in the frontal lobe and temporal lobe of the brain, with sparing of the parietal and occipital lobes. In the over 65 age group, FTLD is probably the fourth most common cause of dementia after Alzheimer s disease, dementia with Lewy bodies and vascular dementia. In the below 65 age group, it is the second most common cause after Alzheimer s disease. In some patients the symptoms of FTLD and Alzheimer s may overlap so what your was surffering either of the two 1 fast withdrawal of lonzep ...with withdrawal symptoms with anger and more agitation or 2 neuroleptic malignant syndrome from qutan more fast dementia means more urinary incontinence.....such medications are sometimes important and sometimes are totally useless....it just weighing of the benefits or side effects or medcinies that you have to decide.....what is better for her wit or with out medicine take care