Hello, Smoking causes permanent changes in your lungs that makes it difficult to breath and at the same time causes easy growth of bacteria that may make your breathing difficulties worse. From what you ve mentioned, it is appearing as though you are suffering from what is known as Acute Exacerbation of Chronic obstructive pulmonary disease, a chronic lung ailment that presents with increase in symptoms periodically. While MoxClav-625 and Deriphylline will be helpful in providing temporary relief, trying to quit smoking will surely help improve your ailments on a more permanent basis. Visit a smoking cessation clinic and try many of the nicotine replacement options that will help you with quitting smoking.