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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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Are High AST, ALt And BP Level During Pregnancy A Cause For Concern?

my wife is in her third trimester of pregnancy.

she had itching problem and LFT was suggested.

The AST and ALT level is higher by 10% and Alkaline phosphate is elevated by 2.5 times the upper limit.

she was having high BP few days back but its normal now.

is there anything to worry
Mon, 23 Feb 2015
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OBGYN, Maternal and Fetal Medicine,  's  Response
Hi, I have gone through your question. In my opinion, your wife is having a condition called intrahepatic cholestasis of pregnancy, which usually develops in the third trimester of pregnancy.In this condition, there is itching specially over palms and soles, and the ALT, AST in the liver function tests are raised.
ALP can sometimes be raised, but it is raised upto 2 times normally in pregnancy.
Since she also has the history of increased BP records, HELLP syndrome in which there is increased BP, hemolysis, elevated liver enzymes and low platelet count needs to be ruled out.
I would suggest you to consult your OBGYN specialist so that examination and appropriate investigations can be done, and prompt treatment can be done for favourable maternal and fetal benefit.
Hope this answers your question.
Wishing you both good health.
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Are High AST, ALt And BP Level During Pregnancy A Cause For Concern?

Hi, I have gone through your question. In my opinion, your wife is having a condition called intrahepatic cholestasis of pregnancy, which usually develops in the third trimester of pregnancy.In this condition, there is itching specially over palms and soles, and the ALT, AST in the liver function tests are raised. ALP can sometimes be raised, but it is raised upto 2 times normally in pregnancy. Since she also has the history of increased BP records, HELLP syndrome in which there is increased BP, hemolysis, elevated liver enzymes and low platelet count needs to be ruled out. I would suggest you to consult your OBGYN specialist so that examination and appropriate investigations can be done, and prompt treatment can be done for favourable maternal and fetal benefit. Hope this answers your question. Wishing you both good health.