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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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Are There Withdarwal Symptoms Associated With Cymbalta Taken For Depression?

I started taking Cymbalta---60 mgs.once a day--- late last summer as a result of depression--just meltdowns and crying jags. It has been a really rough last few years including a divorce and a move to another state after 40+ years in a place I love to a place I dislike, but for family reasons.. Before that I had been taking Citalopram (sp/0 for quite a number of years for the same thing with no side effects and mild to moderate relief. A couple of weeks before Thanksgiving I developed diarrhea like I have never had before---watery and uncontrollable to the point I was afraid to go to sleep at night without an old, heavy towel under me to keep from messing the mattress. i am also very drowsy much of the time and have a terrible time getting up in the morning, often sleep quite late (thank heaven I am retired, age 66, and don t have a daily schedule I must meet. Then I have a terrible time not dosing off in the afternoon. My mood has improved significantly, but no cause has been determined for the diarrhea. I have had blood, urine and stool tests--no infection, though I was put on Cipro for 10 days before the test results came back just in case .. Next is an early colonoscopy. My previous colonoscopies have been normal. I see that diarrhea can be a side effect of Cymbalta, but mine did not appear until a couple of months after I started taking it.. I had no problems at all initially. Now I am just plain depressed by the limitations the diarrhea has put on my life. I am hinking I should go back to the Citalapram, and seeing a counselor I found who will take Medicare, and deep six the Cymbalta. Till now I have not known enough to ask my doctor if there might be a connection, but I plan to ASAP when I can get an appointment, which is usually pretty quickly. What do you think? Are there withdarwal symptoms associated with Cymbalta? I am getting really desperate. I cancelled Thanksgiving with my family and two long planned road trips becaus of this. That, in itself is really depressing and I think my family thinks I am turning into a hypochondriac and I am practically living on Imodium, beside losing 5 pounds,which, in my case, is not at all a good thing. My wight has been very normal since I left high school. Also my blood pressure, normally on the low side---90/68--has gone up to as high as 123/70, very unusual for me and very sudden. This was all very sudden! Thank you in advance, Cynthia Timko.
Mon, 23 Jun 2014
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Psychiatrist 's  Response
HI THANKS FOR YOUR QUERY.READ IT WITH GOOD ATTENTION.I WANT TO CLARIFY ONCE FOR ALL THAT ANTIDEPRESSANTS ARE ASSOCIATED WITH DIARRHEA,CRAMPY ABDOMEN,NAUSEA,VOMITING ETC..ESCITRALOPAM IS A SIMILAR CLASS OF DRUG WITH MINIMAL SIDE EFFECTS..I ADVICE THE LATERTO MY PATIENTS..I ALSO SUGGEST YOU TO ATTEND PSYCHODYNAMIC AND INSIGHT PSYCHOTHERAPEUTIC SESSIONS AND ELECTROCONVULSIVE THERAPY (AS LAST RESORT) FOR BETTER RESULTS AND RESISTANT MAJOR DEPRESSION.I ALSO SUGGEST YOU TO TAKE YOUR LIFE AND RELATIONSHIP IN AN EXTREMELY SPORTIVE AND HEALTHY WAY.THE FLUCTUATIONS IN BLOOD PRESSURE SHOULD BE MONITORED ON REGULAR BASIS CONSIDERING YOUR AGE.I ADVICE YOU TO SCREEN FOR HYPERTENTION AND CONSULT A CARDIOLOGIST.YOUR BP FLUCTUATIONS ARE NOT DRUG RELATED.SO FAR YOUR HEALTH FOLLOWUP HAS BEEN ON A THOROUGH AND A CAREFUL NOTE.AND YOU NEED NOT CALL YOURSELF A HYPOCHONDRIAC.ITS HIGH TIME YOU TAPER YOUR ANTIDEPRESSANTS AND STARTBELEIVING IN NON PHARMACOLOGICAL THERAPIES TO COMBAT YOUR PSYCHOLOGICAL ISSUES.ITS HIGH TIME YOU START ENJOYING YOUR LIFE,BE BRAVE BOLD AND CONFIDENT.MY BEST WISHES..THANK YOU..
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Are There Withdarwal Symptoms Associated With Cymbalta Taken For Depression?

HI THANKS FOR YOUR QUERY.READ IT WITH GOOD ATTENTION.I WANT TO CLARIFY ONCE FOR ALL THAT ANTIDEPRESSANTS ARE ASSOCIATED WITH DIARRHEA,CRAMPY ABDOMEN,NAUSEA,VOMITING ETC..ESCITRALOPAM IS A SIMILAR CLASS OF DRUG WITH MINIMAL SIDE EFFECTS..I ADVICE THE LATERTO MY PATIENTS..I ALSO SUGGEST YOU TO ATTEND PSYCHODYNAMIC AND INSIGHT PSYCHOTHERAPEUTIC SESSIONS AND ELECTROCONVULSIVE THERAPY (AS LAST RESORT) FOR BETTER RESULTS AND RESISTANT MAJOR DEPRESSION.I ALSO SUGGEST YOU TO TAKE YOUR LIFE AND RELATIONSHIP IN AN EXTREMELY SPORTIVE AND HEALTHY WAY.THE FLUCTUATIONS IN BLOOD PRESSURE SHOULD BE MONITORED ON REGULAR BASIS CONSIDERING YOUR AGE.I ADVICE YOU TO SCREEN FOR HYPERTENTION AND CONSULT A CARDIOLOGIST.YOUR BP FLUCTUATIONS ARE NOT DRUG RELATED.SO FAR YOUR HEALTH FOLLOWUP HAS BEEN ON A THOROUGH AND A CAREFUL NOTE.AND YOU NEED NOT CALL YOURSELF A HYPOCHONDRIAC.ITS HIGH TIME YOU TAPER YOUR ANTIDEPRESSANTS AND STARTBELEIVING IN NON PHARMACOLOGICAL THERAPIES TO COMBAT YOUR PSYCHOLOGICAL ISSUES.ITS HIGH TIME YOU START ENJOYING YOUR LIFE,BE BRAVE BOLD AND CONFIDENT.MY BEST WISHES..THANK YOU..