my wife has an undiagnosed disease. Vitamin D deficiency, positive ANA(Not typed, only one test positive) elevated ACE level. She has dermatagraphism, pruiritis, joint pain. Now she is experienving shortness of breath and she feels like her heart is being squeezed. At the doctors office on friday her blood oxygen was 99....so not as worried. Chest CT 4 weeks was clear.....suggestions? Negative for RA, LUPUS .