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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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Can Amitriptyline And Promethazine Be Taken Together For Depression And Anxiety?

Hi there I m suffering frm severe depression n anxiety I collapsed yesterday .cos it was jus too much to handle .it felt like I was overloaded with stress I jus fell down with no energy to hold me up.my Dr gav me amitriptyline as well as promethazine.i want to no if I can take these two together
Mon, 5 Feb 2024
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General & Family Physician,  's  Response
Hello,

Amitriptyline is a tricyclic antidepressant with sedative effects. It is used to treat the symptoms of depression. You can take the medicine prescribed by your treating doctor as per instruction. Promethazine is a phenothiazines and also acts like an antihistamine. Promethazine is used to treat allergy symptoms like itching, runny nose, sneezing, itchy or watery eyes, hives, and itchy skin rashes.

Since you have not mentioned any of allergy symptoms here, you may not take it. Amitriptyline already has sedative effects. Do not take promethazine as it will also cause sedation. You are advised to get connected to a counsellor, group therapy, talk therapy, massage therapy, CBT will help you manage stress and anxiety. Do regular exercises, running and jogging. Take home-made balanced food. Do not skip meals so that your electrolyte level is maintained.

Take care. Hope I have answered your question. Let me know if I can assist you further.

Regards,
Dr. Nupur K., General & Family Physician
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Can Amitriptyline And Promethazine Be Taken Together For Depression And Anxiety?

Hello, Amitriptyline is a tricyclic antidepressant with sedative effects. It is used to treat the symptoms of depression. You can take the medicine prescribed by your treating doctor as per instruction. Promethazine is a phenothiazines and also acts like an antihistamine. Promethazine is used to treat allergy symptoms like itching, runny nose, sneezing, itchy or watery eyes, hives, and itchy skin rashes. Since you have not mentioned any of allergy symptoms here, you may not take it. Amitriptyline already has sedative effects. Do not take promethazine as it will also cause sedation. You are advised to get connected to a counsellor, group therapy, talk therapy, massage therapy, CBT will help you manage stress and anxiety. Do regular exercises, running and jogging. Take home-made balanced food. Do not skip meals so that your electrolyte level is maintained. Take care. Hope I have answered your question. Let me know if I can assist you further. Regards, Dr. Nupur K., General & Family Physician