Hello and Welcome to ‘Ask A Doctor’ service. I have reviewed your query and here is my advice. Allergic reactions to these drugs are not frequent so this is not a good enough reason to reject them. Atenolol may cause both hypotension and bradycardia. Bradycardia is usually more feared than hypotension. You haven t explained your symptoms after increasing Atenolol dosage, so I can t say whether they can be related to the drug or not. Lisinopril may cause hypotension but a patient with hypertension is not very likely to experience such an extreme effect. In most cases the patients do well with those drugs both individually and as a combination. Since your doctor prescribed them for a reason, you d better discuss this matter with him before taking any decisions. I hope you find my comments helpful! Please get back to me if you d like any clarification or more information. Kind Regards!