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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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Can Enalapril And Hydrochlorothiazide Be Taken While On Allopurinol?

I am taking 200 mg of allopurinol a day to manage my gout. I have been taking for about 10 years. I am also taking 20 mg of enalapril and 12.5 mg of hydrochlorthiazide. Both of which are contraindicated with the allopurinol. Been taking for years with yes problem. Should I be concerned. Thanks Tim
Wed, 17 Oct 2018
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Cardiologist 's  Response
Hello,

I would explain that Hydrochlorothiazide may increase uric acid levels. Regarding enalapril, it can lead to allergic reactions when taken concomitantly with allopurinol.

For this reason, I would recommend switching to another drug, like a calcium channel blocker (amlodipine, lercanidipine) for blood pressure control, which does not have this adverse effect.

Hope I have answered your query. Let me know if I can assist you further.

Take care

Regards,
Dr Ilir Sharka, Cardiologist
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Can Enalapril And Hydrochlorothiazide Be Taken While On Allopurinol?

Hello, I would explain that Hydrochlorothiazide may increase uric acid levels. Regarding enalapril, it can lead to allergic reactions when taken concomitantly with allopurinol. For this reason, I would recommend switching to another drug, like a calcium channel blocker (amlodipine, lercanidipine) for blood pressure control, which does not have this adverse effect. Hope I have answered your query. Let me know if I can assist you further. Take care Regards, Dr Ilir Sharka, Cardiologist