Hello,
It's not safe to take these medicines together because of the following harmful interactions:
1. Taking Effexor along with Tramadol can increase the risk for a serious condition called the 'serotonin syndrome' which is characterized by confusion,
hallucination, seizure,
high blood pressure,
increased heart rate, fever,
excessive sweating,
blurred vision, muscle stiffness, tremor, stomach cramp, nausea, vomiting, and diarrhea. Taking Tramadol with Effexor may also increase the risk for seizures not related to the serotonin syndrome.
2. Taking Effexor along with Horizant and Tramadol may increase side effects such as dizziness, drowsiness, confusion, and difficulty concentrating. It may also experience impairment in thinking, judgment, and motor coordination which may result in falls and injuries.
3. Taking Effexor along with Meloxicam may increase the risk of bleeding.
In view of the above, you need to consult your doctor for alternate effective medicines or to make appropriate dose adjustment to prevent these harmful interactions.
Hope I have answered your query. Let me know if I can assist you further.
Regards,
Dr. Mohammed Taher Ali