Can Losartan cause bladder spasms and UTi in women? I started taking it on Monday, Dec 17, 2012, and on Friday I had bladder spasms that felt like I was being turned inside out and like I needed to urinate even though nothing was in my bladder. Two weeks later I have a raging UTI with blood , and it did not respond to treatment with Cipro or Bactrim . I am now on Keflex. If I stop taking the Losartan, will these symptoms disappear?