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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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Can Lupron Usage Lead To Increased AST And ALT Levels?

I am receiving Lupron injections every 3 months for prostate cancer. I had radiation therapy 8 weeks in Sept-Nov 2013. Just recently, my AST and ALT levels doubled in one month. I am going to be retested, but I wondered if Lupron could be a cause of liver problems. I also have renal insufficiency.
Thu, 28 May 2015
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General & Family Physician,  's  Response
Hello,
I read your question carefully and understand your concern very well.

I would like to tell you that Lupron injections are commonly given in prostate cancer and it has its own side effects, but no documentary evidence of liver injury till date, so chances of connection between your elevated liver enzymes and lupron injections are very very unlikely.

I would recommend you to go for ultrasound of abdomen and find out the cause of elevated liver enzymes. You can consult a hepatologist or gastroenterologist for further evaluation and act accordingly.

Hope this will help you and feel free to ask any of your further relevant queries.
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Can Lupron Usage Lead To Increased AST And ALT Levels?

Hello, I read your question carefully and understand your concern very well. I would like to tell you that Lupron injections are commonly given in prostate cancer and it has its own side effects, but no documentary evidence of liver injury till date, so chances of connection between your elevated liver enzymes and lupron injections are very very unlikely. I would recommend you to go for ultrasound of abdomen and find out the cause of elevated liver enzymes. You can consult a hepatologist or gastroenterologist for further evaluation and act accordingly. Hope this will help you and feel free to ask any of your further relevant queries.