Hi! The FDA guidelines on Miralax limit its usage to just 7 days. There is some evidence that long term use of Miralax might result in neuropsychiatric symptoms like memory disorders, cognitive defects etc. However on the other hand there is a lot of internet testimony favoring its use over the long term with at least one scientific paper published in 2006 where it was found safe for use for up to a year. My view is that you should give a serious try to non-drug therapy of constipation including fibre rich foods (like pears), plenty of fluids, exercise etc. before settling down for any kind of long term laxative use. In case you absolutely have to, please involve your healthcare provider in the decision making process. All the best!