Hello, Short answer: No definite conclusion yet but use if benefits outweigh risks. Detailed answer: I understand your concern very well and I will try to give you a complete answer. There is insufficient information regarding the effects (if any) of ADHD drugs on fetal health. The latest scientific papers point out that the number of studies addressing this issue is very low and the designs of available studies do not allow to draw temporal (cause-effect) conclusions. However, the issue is becoming increasingly important since ADHD drugs use during pregnancy is increasing as well. Vyvanse (lisdexamfetamine dimesylate) crosses the placenta but there are no data about its effects on fetus and newborns. Most data come from pregnant women using amphetamines, and there was no evidence of congenital malformations or other harms to fetus. To conclude: more research is needed due to inconclusive data, but the information to date (incomplete) has not shown direct links between ADHD drugs and congenital malformations. Therefore, the advice is that Vyvanse has to be used only if the benefits outweigh the risks. That means that if there is no other way to dominate the health condition of your daughter, then she will use Vyvanse even during pregnancy. In case she will continue to use it, it is important to stick to recommended doses and not to use high doses, as some studies in animals have linked excessive use of parenteral (intramscular or intravenous) amphetamines (about 6 times the normal human dose) with congenital malformations in mice but oral amphetamines (1.5 to 8 times the normal human dose) did not adversely affect fetal development in mice and rabbits. There is no direct correlation between effects in animals and effects in humans, but just to be safe your daughter should not use high doses of Vyvanse but rather follow doctor s recommendations. Hope I have answered your query. Let me know if I can assist you further. Regards, Dr. Ervin Toçi