Hello! The otic drops can t be a concern during pregnancy since they are used locally in the ear and don t enter the blood circulation. Cefuroxime and acetaminophen ar eboth considered in pregnancy category B. There are five pregnancy risk categories of drugs. Category A and B are safe to use during pregnancy, category A is supported by studies in pregnant women, and category B by studies in animals, there are no effects reported in humans but there aren t studies available in humans for category B. Eventhough category B drugs are considered safe to use during pregnancy. As you see, you can bring yourself at ease because there isn t a great deal to concern about. I hope i have been of help.