Can cortisone injections affect your menstrual cycle? I had FOUR in November and shortly after, my menstrual cycle hasn't been the same. Basically had a period for almost two months and then stopped briefly (a few days) and then started back and that's with a little inbetween. Then recently stopped for about 10 days and now full period again. From what I'm reading, this seems to happen to some people. I'm not exactly a big person to begin with. All of about 106lbs and I don't know why the doctor would give me so many and not even discuss the side effects. After I received them, I didn't feel well. Immediately after. Well within about 5 minutes. Had to lay down for a while. Anyway, is this somewhat normal? Thank you