Hi, Thankyou for contacting HCM The reason for persistence of UTI after treatment & repeated recurrence can be due to: 1. Inadequate duration of treatment 2. Inappropriate dosage of the medications 3. Inappropriate selection of antibiotics against the causative organism. 4. Improper treatment of underlying cause of the UTI. Under such circumstances, the following corrective measures should be taken: 1. Discuss regarding the adequate duration of treatment with your treating physician. 2. Discuss regarding the proper dosage of medications depending your age and body weight. 3. Culture & sensitivity of the urine to be done for selection of appropriate antibiotic. 4. Additional investigations like X ray KUB (Kidney Ureter & Bladder) and Ultrasound scan of abdomen & pelvis will be helpful in detecting any hidden focus of infection in the Genito urinary tract. 5.Take ciprofloxacin 500mg twice daily for 5-7days. OR take anyother antibiotic according to the culture sensitivity result. 6.Take urine alkylizers like cranmax sachet twice daily in 1 glass water. 7.Most of the time unhygienic conditions like public washrooms can b the leading cause of recurrent UTI ,therefore avoid such conditions. BUT in your case i would prefer you to get her KUB scan done with full bladder to rule out calculi as cause of pain. X-ray KUB may also be required. Hope this answers your question. If you have additional questions or follow up questions then please do not hesitate in writing to us. Wishing you good health.