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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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Can Taking Zyven OD Be Safe For Depression?

Good After Noon Doctor,I was suffering from depression last 7yeasrs due to big loss in Share mkt,My doctor has been stated give me medicecine blood press and anti depression(MDDR) .currently I am taking only zyven OD plus but when I will not take this medicen in a day ..I will start eating food,drinking coldrinks and I am not feel stable,i legs and arm became heavy ..some shivering on face ...please advice
Mon, 10 Nov 2014
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Psychiatrist 's  Response
Hello
Thanks for asking

You have lost big in share market about 7 years back and then developed depressive symptoms. You are taking Zyven OD (Dexvenlafaxine) for major depressive disorder. The symptoms you are having when you miss a dose are due to withdrawal syndrome of desvenlafaxine. The drug is SNRI drug and abrupt stoppage after chronic use may cause withdrawal symptoms like anxiety. dizziness, instability of gait, tremors of arms and shivering on face. The symptoms you are having are due to withdrawal only. Over all drug use is safe.

As per my opinion don't miss a dose, regular therapy is must for treatment. Other drugs like Mirtazapine, Bupropion (as augment drug) can also prove useful because these drugs have relatively long half life and withdrawal is not so severe.
Take plenty of water and diets rich in proteins and carbohydrates. Fat intake should be less in diet.


Thanks, hope this helps you.
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Can Taking Zyven OD Be Safe For Depression?

Hello Thanks for asking You have lost big in share market about 7 years back and then developed depressive symptoms. You are taking Zyven OD (Dexvenlafaxine) for major depressive disorder. The symptoms you are having when you miss a dose are due to withdrawal syndrome of desvenlafaxine. The drug is SNRI drug and abrupt stoppage after chronic use may cause withdrawal symptoms like anxiety. dizziness, instability of gait, tremors of arms and shivering on face. The symptoms you are having are due to withdrawal only. Over all drug use is safe. As per my opinion don t miss a dose, regular therapy is must for treatment. Other drugs like Mirtazapine, Bupropion (as augment drug) can also prove useful because these drugs have relatively long half life and withdrawal is not so severe. Take plenty of water and diets rich in proteins and carbohydrates. Fat intake should be less in diet. Thanks, hope this helps you.