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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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Cellular And Deep Penetrating Fibrous Histiocytoma, CD43 Positive In Blood Vessels. Cancer?

I have recently been told that a lesion removed from my leg is cellular and deep penetrating fibrous histiocytoma.
My doctor wants to do a wider excision of the area again. He said he is confident about the outcome but local recurrence can happen. Is this cancer? It said in the report it was CD43 positive in blood vessels.
Wed, 23 Oct 2013
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Oncologist, Surgical 's  Response
Fibrous histiocytoma is a type of tumor that does not spread to other parts of the body. However it is a locally aggressive tumor and recurs locally even after adequate surgery. So, recurrence at the same site after inadequate surgery is almost sure shot. Thus, a wide excision of the area is mandatory. As, i said, local recurrence can still happen, but the chances are much less. CD 43 positivity in this setting means nothing and doesnt change either the outcome or the treatment plan.
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Cellular And Deep Penetrating Fibrous Histiocytoma, CD43 Positive In Blood Vessels. Cancer?

Fibrous histiocytoma is a type of tumor that does not spread to other parts of the body. However it is a locally aggressive tumor and recurs locally even after adequate surgery. So, recurrence at the same site after inadequate surgery is almost sure shot. Thus, a wide excision of the area is mandatory. As, i said, local recurrence can still happen, but the chances are much less. CD 43 positivity in this setting means nothing and doesnt change either the outcome or the treatment plan.